Results 71 to 80 of about 114,428 (345)
Endurance training facilitates myoglobin desaturation during muscle contraction in rat skeletal muscle. [PDF]
At onset of muscle contraction, myoglobin (Mb) immediately releases its bound O2 to the mitochondria. Accordingly, intracellular O2 tension (PmbO2) markedly declines in order to increase muscle O2 uptake (mVO2).
Furuichi, Yasuro+9 more
core +1 more source
A novel physiological role for cardiac myoglobin in lipid metabolism
Continuous contractile activity of the heart is essential and the required energy is mostly provided by fatty acid (FA) oxidation. Myocardial lipid accumulation can lead to pathological responses, however the underlying mechanisms remain elusive.
U. Hendgen-Cotta+7 more
semanticscholar +1 more source
Development of an efficient mice model of cancer‐associated cardiac cachexia
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong+9 more
wiley +1 more source
The current work demonstrates the design, characterization, and preparation of molecularly imprinted microspheres for the selective detection of myoglobin in serum samples.
Rüstem Keçili
doaj +1 more source
Catalytic Reduction of Bisulfite by Myoglobin/Surfactant Films [PDF]
The voltammetry of bisulfite at a film formed with myoglobin was studied in aqueous solutions. A broad wave was observed for the reduction of bisulfite.
Abdellatty, Radalla+2 more
core +1 more source
Ultrafast myoglobin structural dynamics observed with an X-ray free-electron laser
Light absorption can trigger biologically relevant protein conformational changes. The light-induced structural rearrangement at the level of a photoexcited chromophore is known to occur in the femtosecond timescale and is expected to propagate through ...
M. Levantino+9 more
semanticscholar +1 more source
Physics of Protein Aggregation in Normal and Accelerated Brain Aging
Soluble monomeric proteins precipitate via nucleation into insoluble amyloids in response to age‐related exposures (e.g., microbes, nanoparticles). Persistent soluble‐to‐insoluble phase transition depletes the functional proteins. In normal aging, replacement matches loss; in accelerated aging, it does not.
Alberto J. Espay+9 more
wiley +1 more source
Background Fructose-mediated protein glycation (fructation) has been linked to an increase in diabetic and cardiovascular complications due to over consumption of high-fructose containing diets in recent times.
Hardik Ghelani+3 more
doaj +1 more source
ABSTRACT There is increasing interest in the development of intensified processes that can provide significant reductions in manufacturing costs for monoclonal antibody (mAb) products. This study examines the performance of an integrated membrane process that combines single‐pass tangential flow filtration (SPTFF) with high‐performance countercurrent ...
Mirko Minervini+4 more
wiley +1 more source
Development of methods for capillary isoelectric focusing of dairy proteins : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Chemistry at Massey University [PDF]
Capillary Isoelectric Focusing (CIEF) is a high-resolution technique which can be applied to the separation and characterisation of complex biological mixtures such as dairy proteins.
Gapper, Leyton William
core