Results 81 to 90 of about 117,263 (356)

Site-Directed Mutagenesis of Myoglobin for Studies of Their Interaction with Iron(III) by Multi-Spectroscopic Techniques

open access: yesJournal of Spectroscopy, 2013
In order to investigate how the amino acids on the surface of myoglobin molecule influence myoglobin's structure and function, a variety of spectroscopy techniques were applied in the study of the interaction between Fe(III) and myoglobin (wild type and ...
Qian Tang   +6 more
doaj   +1 more source

Towards Quantitative Classification of Folded Proteins in Terms of Elementary Functions

open access: yes, 2010
A comparative classification scheme provides a good basis for several approaches to understand proteins, including prediction of relations between their structure and biological function. But it remains a challenge to combine a classification scheme that
Andrei Krokhotin   +4 more
core   +1 more source

Random Walks on a Fluctuating Lattice: A Renormalization Group Approach Applied in One Dimension [PDF]

open access: yes, 1994
We study the problem of a random walk on a lattice in which bonds connecting nearest neighbor sites open and close randomly in time, a situation often encountered in fluctuating media.
A. Bunde   +22 more
core   +1 more source

A novel physiological role for cardiac myoglobin in lipid metabolism

open access: yesScientific Reports, 2017
Continuous contractile activity of the heart is essential and the required energy is mostly provided by fatty acid (FA) oxidation. Myocardial lipid accumulation can lead to pathological responses, however the underlying mechanisms remain elusive.
U. Hendgen-Cotta   +7 more
semanticscholar   +1 more source

Chemical Approaches for Array Based Detection of Amyloids

open access: yesAdvanced Sensor Research, EarlyView.
Amyloids are protein aggregates with both pathological and functional roles. Their detection is challenged by structural polymorphism, isoform diversity, and dynamic aggregation behavior. This review presents chemical array‐based sensing strategies that address these complexities, emphasizing fluorescence and colorimetric methods, alongside ...
Paulo M. Simon, Yijia Xu, Amandeep Kaur
wiley   +1 more source

Post Harvest Discoloration of Dark-Fleshed Fish Muscle: A Review

open access: yesWalailak Journal of Science and Technology, 2011
Discoloration of dark-fleshed fish species during storage and processing was mainly due to the reaction of myoglobin, a monomeric globular heme protein contributed to the pigmentation of red meat fish, alone and with other muscle components. Metmyoglobin
Manat CHAIJAN, Worawan PANPIPAT
doaj   +1 more source

Ultrafast myoglobin structural dynamics observed with an X-ray free-electron laser

open access: yesNature Communications, 2015
Light absorption can trigger biologically relevant protein conformational changes. The light-induced structural rearrangement at the level of a photoexcited chromophore is known to occur in the femtosecond timescale and is expected to propagate through ...
M. Levantino   +9 more
semanticscholar   +1 more source

AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists

open access: yesAdvanced Science, EarlyView.
De novo GLP‐1RAs can be computationally designed to exhibit extended half‐life and superior efficacy compared to Semaglutide. Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and ...
Ting Wei   +13 more
wiley   +1 more source

Review of centrifugal liquid-liquid chromatography using aqueous two-phase solvent (ATPS) systems: Its scale-up and prospects for the future production of high-value biologics [PDF]

open access: yes, 2007
The future challenges in bioprocessing include developing new downstream processes for the purification and manufacture of the protein based medicines of the future to relieve the predicted bottleneck being produced by increasingly high titres from ...
Sutherland, I A
core  

Site-specific incorporation of phosphotyrosine using an expanded genetic code. [PDF]

open access: yes, 2017
Access to phosphoproteins with stoichiometric and site-specific phosphorylation status is key to understanding the role of protein phosphorylation.
Allison Wong   +36 more
core   +1 more source

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