Results 31 to 40 of about 153,900 (312)

Human PrimPol mutation associated with high myopia has a DNA replication defect [PDF]

, 2014
PrimPol is a primase-polymerase found in humans, and other eukaryotes, involved in bypassing lesions encountered during DNA replication. PrimPol employs both translesion synthesis and repriming mechanisms to facilitate lesion bypass by the replisome ...
Aguilera, Aidan J. Doherty, Benjamin A. Keen, Bianchi, Biertümpfel, Brissett, Brown, Donigan, Garcia-Gomez, Iyer, Jones, Keen, Laura J. Bailey, Li, Lobley, Morgan, Mourón, Nemec, Nemec, Pitcher, Rudd, Sale, Saw, Stanislaw K. Jozwiakowski, Vitale, Wan, Washington, Zhao   +27 more
core   +1 more source

Add-On Effect of 0.01% Atropine in Orthokeratology Wearers for Myopia Control in Children: A 2-Year Retrospective Study

Ophthalmology and Therapy, 2023
Introduction Orthokeratology (OK) and low-concentration atropine are recommended approaches for controlling myopia. However, children with younger age and lower myopia are more likely to experience rapid axial progression during OK or atropine ...
Linlin Du, Jun Chen, Li Ding, Jingjing Wang, Jinliuxing Yang, Hui Xie, Xun Xu, Xiangui He, Mengjun Zhu   +8 more
doaj   +1 more source

A retinoscopic survey of 333 horses and ponies in the UK [PDF]

, 2014
Introduction: Ophthalmic examination in the horse is generally limited to crude assessment of vision and screening for ocular lesions. The refractive state of equine eyes and the potential impact on vision and performance requires further ...
Chung, Coile, Corboy, Davidson, Duval, Evans, Flitcroft, Gaiddon, Gordon, Graham, Grinninger, Harman, Howlett, Kinney, McClatchey, McMullen, Michau, Miller, Murphy, Murphy, Mutti, Norton, Ofri, Owens, Rose, Rosenfield, Rull-Cotrina, Saunders, Sekuler, Sivak, Smith, Svaldenienė, Timney, Weale, Wong, Wright, Young, Young, Zadnik   +38 more
core   +1 more source

PDK2-enhanced glycolysis aggravates fibrosis via IL11 signaling pathway in Graves’ orbitopathy

Frontiers in Immunology
ObjectivesTransforming growth factor β1 (TGFβ1)-interleukin 11 (IL11) is a newly found critical signaling pathway in fibrotic diseases such as Graves’ orbitopathy (GO).
Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Zhiyu Peng, Rui Huang, Rui Huang, Rui Huang, Lu Gan, Lu Gan, Lu Gan, Jinghan Wang, Jinghan Wang, Jinghan Wang, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Jie Ding, Jie Ding, Jie Ding, Yinan Han, Yinan Han, Yinan Han, Jihong Wu, Jihong Wu, Jihong Wu, Kang Xue, Kang Xue, Kang Xue, Jie Guo, Jie Guo, Jie Guo, Rui Zhang, Jiang Qian, Ruiqi Ma, Ruiqi Ma, Ruiqi Ma   +35 more
doaj   +1 more source

Evaluation of the Efficacy and Safety of Satralizumab in a Pregnant NMOSD Patient With AQP4/MOG‐IgG Dual Seropositive: A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley   +1 more source

Agreement between a new optical low coherence reflectometry biometer and an anterior segment optical coherence tomographer

Eye and Vision, 2023
Background To assess agreement of measurements between a new optical low coherence reflectometry (OLCR) biometer (SW-9000, Suoer, Tianjin, China) and a spectral-domain optical coherence tomographer (SD-OCT)/Placido topographer (MS-39, CSO, Florence ...
Yiran Wang, Ting Wan, Luze Liu, Yuyuan Xue, Xinyao Chen, Giacomo Savini, Domenico Schiano-Lomoriello, Xingtao Zhou, Jinjin Yu, Jinhai Huang   +9 more
doaj   +1 more source

Maybe Just a Little Bit Special, After All? [PDF]

, 2014
The attitude—common among tax professionals—that tax is special (mostly because of its supposedly unique complexity), and that special legal rules should apply in the tax context, has been described and excoriated by scholars as tax exceptionalism or ...
Ivarsson, Ylva, Sundell, Gustav
core   +3 more sources

Upconversion Nanoparticles Embedded Photonic Contact Lens for Transepithelial Corneal Crosslinking Using Hyaluronate – Riboflavin Conjugate

Advanced Functional Materials, EarlyView.
A minimally invasive, transepithelial corneal cross‐linking (TE‐CXL) approach is presented using upconversion nanoparticles (UCNPs)‐loaded contact lenses (UCLs), after topical delivery of hyaluronate–riboflavin conjugates. The NIR‐to‐UV/blue light conversion by UCNPs in a UCL can activate riboflavin for TE‐CXL, resulting in the biomechanical strength ...
Gibum Lee, Inhoo Choi, Anara Molkenova, Yengwoo Son, Seungmin Yang, Mina Kwon, Tae‐Im Kim, Ki Su Kim, Sei Kwang Hahn   +8 more
wiley   +1 more source

Peripapillary Vascular Reactivity in Primary Open-Angle Glaucoma With High Myopia by Using Optical Coherence Tomography Angiography

Frontiers in Medicine, 2022
PurposeTo evaluate peripapillary vascular reactivity in primary open-angle glaucoma (POAG) with and without high myopia (HM) by using optical coherence tomography angiography (OCTA).MethodsThis prospective study enrolled 48 eyes with POAG, including 16 ...
Xintong Fan, Xintong Fan, Xintong Fan, Xintong Fan, Huan Xu, Huan Xu, Huan Xu, Huan Xu, Ruyi Zhai, Ruyi Zhai, Ruyi Zhai, Ruyi Zhai, Qilian Sheng, Qilian Sheng, Qilian Sheng, Qilian Sheng, Yanan Sun, Yanan Sun, Yanan Sun, Yanan Sun, Tingting Shao, Tingting Shao, Tingting Shao, Tingting Shao, Xiangmei Kong, Xiangmei Kong, Xiangmei Kong, Xiangmei Kong   +27 more
doaj   +1 more source

Universal Electronic‐Structure Relationship Governing Intrinsic Magnetic Properties in Permanent Magnets

Advanced Functional Materials, EarlyView.
Permanent magnets derive their extraordinary strength from deep, universal electronic‐structure principles that control magnetization, anisotropy, and intrinsic performance. This work uncovers those governing rules, examines modern modeling and AI‐driven discovery methods, identifies critical bottlenecks, and reveals electronic fingerprints shared ...
Prashant Singh
wiley   +1 more source