Results 131 to 140 of about 199,830 (310)

Effect of Catechins on the Physicochemical, Structural and Gel Properties of Myosin in Tilapia

open access: yesShipin gongye ke-ji
This study investigated the influence of different mass concentrations of catechin (0~1.00 mg/mL) on the physicochemical characteristics, structures, and gel properties of myosin, through analyses of the turbidity, particle size, Zeta potential, surface ...
Yuyu HANG, Yang ZHANG, Du TAN, Yaqin HU
doaj   +1 more source

3D Bioprinted Blood–Brain–Tumor Barrier Spheroid‐Based In Situ Evaluation of Anticancer Compounds Against Glioblastoma: ROS‐Producing Ruthenium as a Potential Therapeutic Candidate

open access: yesAdvanced Science, EarlyView.
The blood–brain–tumor barrier (BBTB) penetration by anticancer drugs and their effects on glioblastoma (GBM) is assessed using 3D bioprinted‐spheroids. Anticancer drug‐induced U‐87 MG cell death is quantified through in situ imaging of spheroids using a cancer cell death probe. The Ru compound, a partial P‐gp substrate, induces greater tumor‐cell death
Hyunjung Lee   +5 more
wiley   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

The order of things: phosphate release or the power stroke, which does actomyosin do first?

open access: yesFrontiers in Physiology
Myosins are a highly conserved super family of motor proteins that are responsible for driving a host of intracellular processes in eukaryotes, from muscle contraction to vesicular transport.
Edward P. Debold   +2 more
doaj   +1 more source

RBMS1 Contributes to Early Arteriovenous Fistula Neointimal Remodeling Through Modulation of VSMC Phenotypic Responses

open access: yesAdvanced Science, EarlyView.
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li   +14 more
wiley   +1 more source

Myosin - actin filament contraction

open access: yes, 2014
Figure produced to illustrate the role of myosin regulatory light chain (RLC) kinase in the contraction of actin filaments indueced by movement of myosin.
Andrew Marsh (568330)
core   +1 more source

Regulation of Actin-Myosin Interaction by Reversible Phosphorylation of Myosin and Myosin Kinase

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1982
R S, Adelstein   +4 more
openaire   +2 more sources

Plasma Membrane Lipid Asymmetry Dynamically Regulates Passive Diffusion

open access: yesAdvanced Science, EarlyView.
Passive diffusion enables hydrophobic molecules to cross the plasma membrane and exert their biological functions. This study demonstrates that plasma membrane lipid asymmetry, dynamically regulated by lipid scrambling, determines membrane permeability to lipophilic molecules and thereby modulates their cellular activities.
Jieming Ping   +4 more
wiley   +1 more source

The Regulatory Mechanism of Myosin Phosphorylation during Mitosis: The Cell Cycle-Dependent Control of Myosin Light Chain Kinase and Myosin Phosphatase [PDF]

open access: yes
Table of Contents / p2 1. General Abstract / p3 2. General Introduction / p5 3. Chapter1:Mitosis-specific Phosphorylation of Smooth Muscle Regulatory Light Chain of Myosin II at Ser-1 and/or -2 and Thr-9 in Sea Urchin Egg Extract. / p8 4.
Totsukawa, Go
core   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman   +3 more
wiley   +1 more source

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