Results 151 to 160 of about 380,707 (403)
Advanced Science, EarlyView.The E3 ubiquitin ligase RFWD3 binds the exonuclease TREX1 and protects it from TRIM24‐mediated ubiquitination and degradation, leading to the eradication of intracellular dsDNA, inhibition of the cGAS‐STING pathway, and immunosuppressive microenvironment of lung cancer.
Xue‐Yan Shi +12 more
wiley +1 more source
Familial Hypertrophic Cardiomyopathy: Diagnosis and Management
Vascular Health and Risk Management, 2023 Michael J Litt,1 Ayan Ali,2 Nosheen Reza1 1Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; 2Department of Medicine, Perelman School of Medicine at the ...
Litt MJ, Ali A, Reza N
doaj
Force-Dependent Stepping Kinetics of Myosin-V [PDF]
, 2005 Anabel E.‐M. Clemen +5 more
openalex +1 more source
Advanced Science, EarlyView.Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao +4 more
wiley +1 more source
Reconstituted Human Myosin Light Chain Phosphatase Reveals Distinct Roles of Two Inhibitory Phosphorylation Sites of the Regulatory Subunit, MYPT1 [PDF]
, 2014 Mukta D. Khasnis +3 more
openalex +1 more source
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
Advanced Science, EarlyView.This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source
Myosins XI-K, XI-1, and XI-2 are required for development of pavement cells, trichomes, and stigmatic papillae in Arabidopsis [PDF]
, 2012 Eve‐Ly Ojangu +6 more
openalex +1 more source
The sedimentation of myosin [PDF]
Biochemical Journal, 1960 P, JOHNSON, A J, ROWE
openaire +2 more sources
Advanced Science, EarlyView.Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang +18 more
wiley +1 more source
Nuclear myosin 1 contributes to a chromatin landscape compatible with RNA polymerase II transcription activation [PDF]
, 2015 Bader Almuzzaini +3 more
openalex +1 more source