Results 151 to 160 of about 161,523 (294)

Muscle growth by sarcomere divisions. [PDF]

open access: yesSci Adv
Rodier C   +8 more
europepmc   +1 more source

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

Subunit Structure of Myosin

open access: hybrid, 1969
Lewis C. Gershman   +2 more
openalex   +1 more source

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan   +3 more
wiley   +1 more source

Myosin inhibitors for treatment of hypertrophic cardiomyopathy. [PDF]

open access: yesCochrane Database Syst Rev
Quill S   +6 more
europepmc   +1 more source

Characterization of Cardiac Myosin from the Dog

open access: hybrid, 1964
Helmut Mueller   +3 more
openalex   +1 more source

Generation of Clonal Cultures of Adherent or Suspension Cells Using Flat Sessile Drops for Assurance of Monoclonality

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Single‐cell isolation is an essential step in many biomedical workflows, including genetic analyses and drug‐based assays. It is commonly attempted through limiting dilution into microtiter wells. However, dark optical edge effects at the well periphery make it difficult to confirm which wells contain just one cell.
Joseph A. E. Morgan   +3 more
wiley   +1 more source

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