Molecular motors robustly drive active gels to a critically connected state
Living systems often exhibit internal driving: active, molecular processes drive nonequilibrium phenomena such as metabolism or migration. Active gels constitute a fascinating class of internally driven matter, where molecular motors exert localized ...
A Clauset +60 more
core +1 more source
A micro-volume adaptation of a stopped-flow system; use with μg quantities of muscle proteins [PDF]
Stopped-flow spectroscopy is a powerful method for measuring very fast biological and chemical reactions. The technique however is often limited by the volumes of reactants needed to load the system.
Behrens, Vincent +4 more
core +1 more source
Direct Regulation of Striated Muscle Myosins by Nitric Oxide and Endogenous Nitrosothiols [PDF]
, both through activation of guanylyl cyclase and through modification of cysteines in proteins to yield S-nitrosothiols. While NO affects the contractile apparatus directly, the identities of the target myofibrillar proteins remain unknown.
A Gow +43 more
core +2 more sources
Expression in Escherichia coli of fragments of the coiled-coil rod domain of rabbit myosin: influence of different regions of the molecule on aggregation and paracrystal formation [PDF]
We have expressed in Escherichia coli a cDNA clone corresponding broadly to rabbit light meromyosin (LMM) together with a number of modified polypeptides and have used this material to investigate the role of different aspects of molecular structure on ...
Atkinson, Simon J, Stewart, Murray
core
Characterization of recessive RYR1 mutations in core myopathies [PDF]
We have characterized at the molecular level, three families with core myopathies carrying apparent recessive mutations in their RYR1 gene and studied the pharmacological properties of myotubes carrying endogenous mutations as well as the properties of ...
Bertini, Enrico +10 more
core
Making Muscle Elastic: The Structural Basis of Myomesin Stretching [PDF]
The muscle M-band protein myomesin comprises a 36-nm long filament made of repetitive immunoglobulin–helix modules that can stretch to 2.5-fold this length, demonstrating substantial molecular ...
A Fukuzawa +42 more
core +4 more sources
Electrode measurements of the net charge on muscle proteins [PDF]
Electrode techniques for measuring Donnan potentials in protein solutions were studied and applied to elucidate the effect of methylation on the net charge of heavy meromyosin (HMM) and the effect of Ca2+ on the net charge of the thin filament proteins.
Bryson, Elzbieta Anna
core +1 more source
Desarrollo de geles bioactivos basados en residuos de la industria del arroz [PDF]
La industria arrocera produce aproximadamente unos 100 millones de toneladas de residuos cada año. Aunque estos residuos tengan un alto contenido proteico, habitualmente se incineran debido a su alto poder calorífico.
Félix Ángel, Manuel +3 more
core
The sophisticated survival strategies of the pathogen Listeria monocytogenes [PDF]
The function of the ActA protein of Listeria monocytogenes has been partially elucidated. These results illustrate the sophistication with which intracellular pathogens like Listeria use the host cell to their advantage, and have provided new insights ...
Jürgen Wehland, Uwe D. Carl
core +2 more sources

