Results 211 to 220 of about 20,573 (287)

Biomarkers to predict outcomes in diabetic foot ulcers

VIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro, Kellie Fortune, Eimear Daly, Luca McCann, Merhan Soltan, Seamus Sreenan, Fabio Quondamatteo   +6 more
wiley   +1 more source

Actin from within - how nuclear myosins and actin regulate nuclear architecture and mechanics.

J Cell Sci
Gawor M, Lehka L, Lambert D, Toseland CP.   +3 more
europepmc   +1 more source

Effect of soft tissue sample preparation techniques for scanning small‐angle X‐ray scattering experiments

Journal of Synchrotron Radiation, EarlyView.
The effect of tissue‐processing techniques, including fixation and embedding, on the structural information obtained from scanning small‐angle X‐ray scattering of muscle and connective tissue has been studied. This provides a framework for sSAXS users working with soft tissues to make an informed choice on the sample preservation method, tailored to ...
Atreyee Acharya, Arthur Baroni, Irene Rodriguez-Fernandez, Mads Carlsen, Marianne Liebi   +4 more
wiley   +1 more source

The Allosteric Inhibitor Pentachloropseudilin Inhibits Myosin 1C ATPase Activity and Recapitulates Retinitis Pigmentosa Phenotypes in Mice. [PDF]

ACS Omega
Radhakrishnan R, Martin R, Monsanto RDC, Lor A, Gruesen A, Leung M, Roehrich H, Keskin-Yilmaz N, Cureoglu S, Tsuprun V, van Kuijk FJ, Rohrer B, Knölker HJ, Lobo GP.   +13 more
europepmc   +1 more source

Increased energetic cost of movement reduces reproductive output in zebrafish at different temperatures and water flow rates

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Locomotion consumes a large proportion of individual energy budgets and may impose energetic constraints on other fitness‐related traits particularly under variable environmental conditions.
Miki Jahn, Frank Seebacher
wiley   +1 more source

Non-muscle tropomyosins inhibit myosin-19 and dynamically localize to mitochondrially associated actin filaments. [PDF]

J Biol Chem
Thompson CP, Pollard LW, Xu M, Holzbaur ELF, Ostap EM.   +4 more
europepmc   +1 more source

Myosin-dependent short actin filaments contribute to peripheral widening in developing stereocilia. [PDF]

Nat Commun
Liao X, Tung CY, Krey JF, Behnammanesh G, Cirilo JA, Colpan M, Yengo CM, Barr-Gillespie PG, Bird JE, Perrin BJ.   +9 more
europepmc   +1 more source

Altered cytoskeletal integrity underlies impaired platelet shape change and defective thrombus formation in ETV6‐related thrombocytopenia

British Journal of Haematology, EarlyView.
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov, Julia‐Jessica D. Korobkin, Daria V. Fedorova, Sofia V. Galkina, Maria M. Golomysova, Sergei I. Obydennyi, Anastasia A. Ignatova, Ekaterina‐Iva A. Adamanskaya, Eugenia V. Yushkova, Anna V. Pavlova, Pavel A. Zharkov, Igor I. Kireev, Galina A. Novichkova, Viktor G. Zgoda, Mikhail A. Panteleev, Anastasia N. Sveshnikova   +15 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Molecular counting of myosin force generators in growing filopodia. [PDF]

J Biol Chem
Fitz GN, Tyska MJ.
europepmc   +1 more source