Results 101 to 110 of about 73,410 (327)

Impact of evolving treatment patterns on interstitial lung disease progression in systemic sclerosis using the EUSTAR database

Arthritis &Rheumatology, Accepted Article.
Background The treatment landscape for systemic sclerosis‐associated interstitial lung disease (SSc‐ILD) has evolved with increasing immunosuppressive (IST) and anti‐fibrotic therapies available. However, their real‐world use remains unclear. Objectives To analyze treatment trends and the effect of IST and anti‐fibrotic therapies on ILD progression ...
Corrado Campochiaro, Marie‐Elise Truchetet, Madelon Vonk, Giacomo De Luca, Giovanna Cuomo, Lidia P. Ananieva, Eric Hachulla, Vanessa Smith, Ana Maria Gheorghiu, Radim Becvar, Patricia Carreira, Nicolas Hunzelmann, Daniel E. Furst, Vera Ortiz‐Santamaria, Francesco Del Galdo, Marco Matucci‐Cerinic, Anna‐Maria Hoffmann‐Vold, EUSTAR collaborators   +17 more
wiley   +1 more source

Concomitant occurrence of FXTAS and clinically defined sporadic inclusion body myositis: report of two cases. [PDF]

, 2017
This report describes unique presentations of inclusion body myositis (IBM) in two unrelated patients, one male and one female, with genetically and histologically confirmed fragile X-associated tremor/ataxia syndrome (FXTAS).
Bolitho, Samuel J, Gonzales, Hilary, Hagerman, Paul J, Hagerman, Randi J, Hah, Mina, Hunsaker, Michael Ryan, Joffe, Ronald, Lechpammer, Mirna, Martínez Cerdeńo, Verónica, Pamphlett, Roger, Tassone, Flora, Tisch, Steve   +11 more
core   +2 more sources

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

An atypical presentation of immune checkpoint inhibitor associated myositis with normal creatine kinase: a case report

Frontiers in Immunology
Immune checkpoint inhibitors (ICIs) have been revolutionary in the field of cancer therapeutics. Myositis is a known rheumatic immunotherapy related adverse event with a fatality rate of 26.8% when associated with myasthenia gravis and 51.3% when ...
Monika A. Satoskar, Anthony G. Mansour, Richard Wu, Yuanquan Yang, Mary H. Caldwell, Alexa S. Meara, Alexa S. Meara   +6 more
doaj   +1 more source

Atypical Multibacterial Granulomatous Myositis in a Horse: First Report in Italy [PDF]

, 2020
Claudia Rifici, Annarita Attili, Davide De Biase, Roselane Gonçalves dos Santos, Núbia Seyffert, Thiago Luiz de Paula Castro, Henrique César Pereira Figueiredo, Carmelo Scaramozzino, Stefano Reale, Orlando Paciello, Vincenzo Cuteri, Sharon J. Spier, Vasco Azevedo, G. Mazzullo   +13 more
openalex   +1 more source

Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma

Clinical Pharmacology &Therapeutics, EarlyView.
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg, Maaike M. Hofman, Fatima Ashad, Alaa Daloul, Stefani Oosterveld, Edwin A. Basak, Esther Oomen‐de Hoop, Astrid A. M. van der Veldt, Arjen Joosse, Roelof W. F. van Leeuwen, Ron H. J. Mathijssen   +10 more
wiley   +1 more source

Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]

, 2013
Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core   +3 more sources

Muscle Ultrasound Echo Intensity Detects Insulin Resistance Before Changes in HbA1c or Fasting Glucose, Independent of BMI

Journal of Ultrasound in Medicine, EarlyView.
Objectives To quantify the association between skeletal muscle echo intensity (MEI), measured by ultrasound, and clinical markers of insulin resistance and glycemic control, and evaluate MEI's diagnostic accuracy in identifying insulin resistance. Methods In this cross‐sectional study, 20 adults with obesity (mean body mass index [BMI] 34.4 ± 2.6 kg/m2,
Steven B. Soliman, Jacob E. Leuteneker, Olivia K. Chugh, Tao Zhang, Becca Tuska, Thomas Rode, Maria J. Sanchez, Eric D. Buras, Jeffrey F. Horowitz   +8 more
wiley   +1 more source

Myositis Basics/Who Gets Myositis

, 2019
The idiopathic inflammatory myopathies (IIM), often referred to collectively but less specifically as “myositis,” have an estimated prevalence of ~14 per 100,000 with an annual incidence of ~8 per 1,000,000 population, which appears to be increasing over time. Any age group can be affected, but myositis commonly presents between 30 and 60 years of age.
Parker, Matthew J. S., Chinoy, Hector, Cooper, Robert G., Lamb, Janine A.   +3 more
openaire   +1 more source

Prevalence of the E321G MYH1 variant for immune-mediated myositis and nonexertional rhabdomyolysis in performance subgroups of American Quarter Horses. [PDF]

, 2019
BackgroundImmune-mediated myositis (IMM) in American Quarter Horses (QHs) causes acute muscle atrophy and lymphocytic infiltration of myofibers. Recently, an E321G mutation in a highly conserved region of the myosin heavy chain 1 (MYH1) gene was ...
Finno, Carrie J, Gardner, Keri, Gianino, Giuliana M, Henry, Marisa L, Penedo, Cecilia, Perumbakkam, Sudeep, Valberg, Stephanie J   +6 more
core   +2 more sources