Results 91 to 100 of about 26,633 (217)

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

Experimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su, Na Liu, Yang Liu, Yiqun Sun, Yike Jiao   +4 more
wiley   +1 more source

Preliminary investigation into a potential role for myostatin and its receptor (ActRIIB) in lean and obese horses and ponies.

PLoS ONE, 2014
Obesity is a widespread problem across the leisure population of horses and ponies in industrialised nations. Skeletal muscle is a major contributor to whole body resting energy requirements and communicates with other tissues through the secretion of ...
Philippa K Morrison, Chen Bing, Patricia A Harris, Charlotte A Maltin, Dai Grove-White, Caroline McG Argo   +5 more
doaj   +1 more source

A myostatin-CCL20–CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis

Scientific Reports, 2021
The interactions of fibroblast-like synoviocyte (FLS)-derived pro-inflammatory cytokines/chemokines and immune cells support the recruitment and activation of inflammatory cells in RA. Here, we show for the first time that the classical myokine myostatin
Michelle Fennen, Toni Weinhage, Vanessa Kracke, Johanna Intemann, Georg Varga, Corinna Wehmeyer, Dirk Foell, Adelheid Korb-Pap, Thomas Pap, Berno Dankbar   +9 more
doaj   +1 more source

Combined sanger and ngs sequence analysis of the myostatin gene (mstn) in the Camelus dromedarius species [PDF]

, 2015
Different mutations have been identified in the myostatin gene (MSTN), some of which are responsible for protein inactivation and double muscling phenotype in mammals.
Burger, P., Cherifi, Y., Ciani, Elena, Faye, Bernard, Fitak, Robert Rodgers, Lacalandra, G.M., Muzzachi, S., Oulmouden, A., Yahyaoui, H., Zayed, M.A.   +9 more
core  

Limited musculoskeletal benefits of artificial gravity combined with cycling during bed rest: Results from the BRACE study

Experimental Physiology, EarlyView.
Abstract Prolonged exposure to microgravity, simulated via 6° head‐down tilt bed rest (HDT), induces musculoskeletal deconditioning and negatively impacts body composition. This study evaluated whether a combination of aerobic exercise with artificial gravity (AG) offers superior protection in comparison to exercise alone.
Mirko Mandić, Tommy R. Lundberg, Jean‐Pol Frippiat, Adam C. McDonnell, Igor B. Mekjavić, Marie‐Pierre Bareille, Rebecca Billette de Villemeur, Rodrigo Fernandez‐Gonzalo   +7 more
wiley   +1 more source

Integrative physiology of skeletal muscle for maintaining cognitive health

The Journal of Physiology, EarlyView.
Abstract figure legend Maintenance of brain/cognitive health and function is increasingly appreciated to be a systemic challenge. In particular, skeletal muscle influences the brain through release of myokines in response to contraction, which influence the expression of brain‐derived neurotrophic factor (BDNF) in the brain, a vital player in the ...
Matthew H. Brisendine, Joshua C. Drake
wiley   +1 more source

Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study

Annals of Clinical and Translational Neurology
Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status.
Fiorella Piemonte, Sara Petrillo, Anna Capasso, Giorgia Coratti, Adele D'Amico, Michela Catteruccia, Maria Carmela Pera, Concetta Palermo, Marika Pane, Emanuela Abiusi, Gianpaolo Cicala, Marianna Villa, Chiara Bravetti, Chiara Arpaia, Agnese Novelli, Salvatore Falqui, Stefania Fiori, Giulia Napoli, Silvia Baroni, Francesco Danilo Tiziano, Enrico Bertini, Giacomo Comi, Stefania Corti, Eugenio Mercuri   +23 more
doaj   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson, Tariq Taylor, Dumitru Constantin‐Teodosiu, Despina Constantin, Martino V. Franchi, Dorothee Auer, Paul L. Greenhaff   +6 more
wiley   +1 more source

A Set of Nonparametric Tests for Experiments with Lattice-Ordered Means: Theory, Programs, and Applications [PDF]

In many factorial experiments where the factors have levels that are ordinal or quantitative, a researcher may predict that the mean response in certain treatments will be higher or lower than those in other treatments.
Hsiao-Pin Liu, Matthew Strand, Shalender Bhasin   +2 more
core   +1 more source

MANDIBULAR SHAPE IN MYOSTATIN-DEFICIENT MICE: A GEOMETRIC MORPHOMETRIC ANALYSIS [PDF]

, 2012
The relationship between muscle function and mandibular morphology is unclear. Manipulating the size or function of muscle and then observing the effect on adjacent bone is one way to explore this relationship.
Johnston, Fayth
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