Results 91 to 100 of about 33,582 (263)
Equine Veterinary Journal, EarlyView.Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska +4 more
wiley +1 more source
Clinical and Molecular Hepatology, 2020 Background/Aims The role of serum myokine levels in sarcopenia and the outcome of hepatocellular carcinoma (HCC) patients are not clear. This study investigated the serum levels of myostatin, follistatin, and interleukin-6 (IL-6) in HCC patients and ...
K. Choi +9 more
semanticscholar +1 more source
Association of myostatin, a cytokine released by muscle, with inflammation in rheumatoid arthritis
Medicine, 2021 Supplemental Digital Content is available in the text Abstract Myostatin is a cytokine produced and released by myocytes that might have an outstanding role not only in muscle wasting during cachexia but also in inflammation.
J. Murillo-Saich +7 more
semanticscholar +1 more source
Nutrition in Clinical Practice, EarlyView.Abstract Background Although previous experimental studies showed that metabolic acidosis promoted muscle catabolism and impaired protein synthesis, few epidemiological studies reported an independent association between serum bicarbonate levels and muscle atrophy in patients with chronic kidney disease (CKD).
Nobuhisa Morimoto +13 more
wiley +1 more source
Cord blood myostatin concentrations by gestational diabetes mellitus and fetal sex
Frontiers in Endocrinology, 2023 IntroductionMyostatin is a member of the transforming growth factor β superfamily, and is mainly secreted from skeletal muscle. Animal studies have demonstrated that deficiency in myostatin promotes muscle growth and protects against insulin resistance ...
Rong Huang +14 more
doaj +1 more source
Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease
Neuroprotection, EarlyView.Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García +7 more
wiley +1 more source
Development of antisense-mediated myostatin knockdown for the treatment of insulin resistance
Scientific Reports, 2021 Myostatin is a negative regulator of muscle mass and its inhibition represents a promising strategy for the treatment of muscle disorders and type 2 diabetes.
Wouter Eilers +2 more
doaj +1 more source
A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood. [PDF]
, 2016 Heterochronic parabiosis rejuvenates the performance of old tissue stem cells at some expense to the young, but whether this is through shared circulation or shared organs is unclear.
Causey, Keith +6 more
core +1 more source
Cells, 2020 Myostatin inhibition therapy has held much promise for the treatment of muscle wasting disorders. This is particularly true for the fatal myopathy, Duchenne Muscular Dystrophy (DMD).
E. Rybalka +5 more
semanticscholar +1 more source
Portal Hypertension &Cirrhosis, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) is a chronic liver disease. Research into a feasible, rapid, and effective assessment method is crucial for evaluating the therapeutic effects of semaglutide in MASLD. This prospective study utilized ultrasound‐derived fat fraction measurement and fat‐to‐muscle ratio to evaluate hepatic ...
Yunlin Huang +10 more
wiley +1 more source