Results 91 to 100 of about 19,108 (217)

Muscle and serum myostatin expression in type 1 diabetes

open access: yesPhysiological Reports, 2020
Type 1 diabetes (T1D) has been reported to negatively affect the health of skeletal muscle, though the underlying mechanisms are unknown. Myostatin, a myokine whose increased expression is associated with muscle‐wasting diseases, has not been reported in
Athan G. Dial   +8 more
doaj   +1 more source

NSAID ingestion augments training‐induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the impact of NSAID ingestion on resistance exercise training‐induced changes in muscle morphology, function and gene networks relative to placebo ingestion in trained males. Abstract Non‐steroidal anti‐inflammatory drugs (NSAIDs) are widely overused in sports.
Joanne E. Mallinson   +6 more
wiley   +1 more source

Myostatin-induced inhibition of the long noncoding RNA Malat1 is associated with decreased myogenesis

open access: yes, 2013
Myostatin, a member of the transforming growth factor-β (TGF-β) superfamily of secreted proteins, is a potent negative regulator of myogenesis. Free myostatin induces the phosphorylation of the Smad family of transcription factors, which, in turn ...
Virginia Johnsen (20029545)   +3 more
core  

Dietary Polyphenols as Regulators of Protein Deposition and Muscle Health: Mechanisms, Interactions, and Functional Applications

open access: yesFood Science &Nutrition, Volume 14, Issue 11, November 2026.
Dietary polyphenols contribute to the regulation of protein deposition and muscle health through multiple interconnected mechanisms. They promote protein synthesis and myogenic differentiation mainly by modulating the PI3K/AKT/mTOR signaling pathway and myogenic regulatory factors, while suppressing excessive protein degradation through regulation of ...
Chen Liu   +6 more
wiley   +1 more source

A New Method of Myostatin Inhibition in Mice via Oral Administration of Lactobacillus casei Expressing Modified Myostatin Protein, BLS-M22

open access: yes, 2022
Myostatin is a member of the transforming growth factor-beta superfamily and is an endogenous negative regulator of muscle growth. This study aimed to determine whether an oral administration of Lactobacillus casei expressing modified human myostatin ...
Lee, Jiwon   +17 more
core   +1 more source

Circulating myostatin is reduced with aging in humans but not altered by short-term, high intensity training [PDF]

open access: yes, 2016
Introduction: Ageing involves a loss of muscle mass and function. The rate of decline is associated with negative health outcomes and increased mortality (1).
Parnell, M.   +11 more
core  

Myostatin binds the amino-terminus of LTBP4.

open access: yes, 2016
(A) Full length (FL), amino terminal (N), and carboxy terminal (C) fragments of LTBP4 were ligated into expression vectors. (B) HEK293T cells were transfected with human LTBP4 and myostatin constructs. Co-immunoprecipitation was performed on cell lysates
Judy U. Earley (371960)   +10 more
core   +1 more source

Univariate regression analysis results for myostatin ELISA data.

open access: yes, 2014
Myostatin concentration was the outcome variable and BCS, myostatin and ActRIIB gene and protein expression data for the individual skeletal muscles was offered as explanatory variables.Univariate regression analysis results for myostatin ELISA data.
Caroline McG. Argo (457164)   +5 more
core   +1 more source

hSGT interacts with the N-terminal region of myostatin

open access: yes, 2003
Myostatin is a new member of the transforming growth factor-β (TGFβ) superfamily and functions as a negative regulator of skeletal muscle growth. Herein, we report the identification of a myostatin-associated protein hSGT (human small glutamine-rich ...
Zhang, Q., Wang, H., Zhu, D.
core   +1 more source

Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways

open access: yes, 2014
Myostatin, a member of the transforming growth factor-β superfamily, is a potent negative regulator of skeletal muscle growth and is conserved in many species, from rodents to humans.
Vernus, Barbara   +8 more
core   +1 more source

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