Results 91 to 100 of about 12,955 (195)

Serum level of myostatin and type I interferon-inducible gene expression in dermatomyositis patients and its relation to insulin resistance

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Data regarding the relation between serum myostatin level, type I interferon-inducible gene expression and insulin resistance in dermatomyositis patients are limited.
Rania S. Nageeb, Noura Mostafa Mohamed, Ahmad Sallam Soliman, Amany M. Ebaid, Nancy Abdelhamid Mohammad   +4 more
doaj   +1 more source

CRISPR/Cas9‐mediated mstnb1 disruption enhances growth in rainbow trout

Journal of the World Aquaculture Society, Volume 57, Issue 4, August 2026.
Abstract The effects of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9‐mediated disruption of the myostatin gene (mstnb1) on the growth performance of rainbow trout (Oncorhynchus mykiss) were evaluated. Two specific guide RNAs (gRNAs) targeting the first exon of the target gene were co‐injected into fertilized eggs.
Abdulkadir Bayır, Mehtap Bayır, Wenjing Tao, Chunfang Wang, Serpil Turhan, Burcu Naz Uzun, Gökhan Arslan, Harun Arslan, Deshou Wang   +8 more
wiley   +1 more source

Correlations of serum myostatin and irisin with sarcopenia and osteoporosis in rheumatoid arthritis patients: a cross-sectional study

Scientific Reports
Myostatin and irisin, the key regulators of muscle metabolism, are myokines secreted by skeletal muscles that significantly influence osteoporosis (OP) and sarcopenia.
Wan-jun Li, Ruo-yan-ran Yin, Xiao-xuan Xia, Qian-xi Xing, Sheng-qian Xu   +4 more
doaj   +1 more source

Divergent skeletal muscle metabolite exchange in insulin‐like growth factor‐1‐stimulated myotubes and resistance‐exercised human muscle

Experimental Physiology, Volume 111, Issue 8, Page 3784-3799, 1 August 2026.
Abstract Skeletal muscle hypertrophy requires a substantial nutrient influx for biomass accretion, but global metabolite exchange during growth is poorly characterized. Therefore, we profiled the metabolite uptake and release in insulin‐like growth factor‐1 (IGF‐1)‐stimulated C2C12 myotubes and human muscle 24 h after resistance exercise ...
Tim Havers, Moritz Eggelbusch, Marius Meinhold, Kira Sing, Rainer Okrojek, Anna Artati, Michael Witting, Dominik Lutter, Claire V. Kieker, Collin Starke, Tushar More, Karsten Hiller, Flemming Dela, Martin Schönfelder, André Kafka, Stephan Geisler, Henning Wackerhage   +16 more
wiley   +1 more source

Mechanical Loading Induces Distinct and Shared Responses in Endothelial and Muscle Cells and Reveals Exercise‐Like Molecular Profiles

The FASEB Journal, Volume 40, Issue 14, 31 July 2026.
Mechanical loading of human endothelial and muscle cells induced several distinct and shared molecular responses, many of which are commonly observed after exercise in vivo. Both cell types secreted acetate and endothelial cells increased serine synthesis from glucose.
Sakari Mäntyselkä, Erik Niemi, Laura Ylä‐Outinen, Kalle Kolari, Liina Uusitalo‐Kylmälä, Alfredo Ortega‐Alonso, Roosa‐Maria Liimatainen, Vasco Fachada, Perttu Permi, Elina Kalenius, Juha J. Hulmi, Riikka Kivelä   +11 more
wiley   +1 more source

Preptin and Myostatin Independently Increase in Pre-Diabetics and Patients of Type 2 Diabetes Mellitus

Acta Medica Iranica, 2019
The relation between serum preptin, myostatin, insulin, and also homeostatic model assessment-insulin resistance were examined in pre-diabetes persons and newly diagnosed patients with overt type 2 diabetes mellitus.
Saeed Nazari Soltan Ahmad, Sajjad Nourollahi, Manouchehr Nakhjavani, Mehran Khojastehfard, Mostafa Mostafazadeh, Hamed Hajipour, Davoud Sanajou   +6 more
doaj  

Creatine/Creatinine Ratio and Myostatin as Biomarkers to Monitor Muscle Function in Duchenne Muscular Dystrophy Patients. [PDF]

J Cachexia Sarcopenia Muscle
Degan C, Tsonaka R, de Vries SI, Ikelaar NA, van der Holst M, Kan HE, Niks EH, Spitali P.   +7 more
europepmc   +1 more source

Targeting Cancer Cachexia: A Mechanistic Evaluation of Anti-GDF-15 Antibody-Based Combination Therapies. [PDF]

J Cachexia Sarcopenia Muscle
Breen DM, Joaquim S, Paulhus BL, Bennett D, Bernardo B, Collins S, Esquejo RM, Kim-Muller JY, Lin L, Peloquin M, Wu Z, Qiao S, Stansfield JC, Zhang BB, Rossulek MI.   +14 more
europepmc   +1 more source

Cellular and molecular pathways linking obesity to skeletal muscle dysfunction. [PDF]

Mol Biol Rep
Pinheiro D, Cornachione AS.
europepmc   +1 more source

Association between vitamin D status and circulating myokines (irisin, myostatin, and myonectin) in children: A cross-sectional study. [PDF]

PLoS One
Buyukinan M, Kurku H, Bagci Z, Gederet YT, Yilmaz AF.   +4 more
europepmc   +1 more source