Results 121 to 130 of about 33,582 (263)
Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study
Annals of Clinical and Translational NeurologyObjective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status.
Fiorella Piemonte +23 more
doaj +1 more source
PLoS ONE, 2014 Obesity is a widespread problem across the leisure population of horses and ponies in industrialised nations. Skeletal muscle is a major contributor to whole body resting energy requirements and communicates with other tissues through the secretion of ...
Philippa K Morrison +5 more
doaj +1 more source
Experimental Physiology, EarlyView.Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti +6 more
wiley +1 more source
Pancreatic cancer cachexia: a review of mechanisms and therapeutics. [PDF]
, 2014 Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer. Unfortunately, its treatment is complex and remains a challenge.
Andrew Eugene Hendifar +8 more
core +2 more sources
In vitro muscle contraction: A technical review on electrical pulse stimulation in C2C12 cells
Experimental Physiology, EarlyView.Abstract Electrical pulse stimulation (EPS) of skeletal muscle cells is increasingly used to model exercise In vitro. The murine C2C12 myotube system has become a common platform for such studies, yet wide variability in EPS protocols hampers reproducibility and cross‐study comparisons.
Mark R. C. van de Meene +4 more
wiley +1 more source
MANDIBULAR SHAPE IN MYOSTATIN-DEFICIENT MICE: A GEOMETRIC MORPHOMETRIC ANALYSIS [PDF]
, 2012 The relationship between muscle function and mandibular morphology is unclear. Manipulating the size or function of muscle and then observing the effect on adjacent bone is one way to explore this relationship.
Johnston, Fayth
core
Communications Biology, 2020 Myostatin (MSTN), associated with the “double muscling” phenotype, affects muscle growth and fat deposition in animals, whereas how MSTN affects adipogenesis remains to be discovered.
H. Ren +16 more
semanticscholar +1 more source
Intramuscular pathways of maladaptation in overtraining syndrome
The Journal of Physiology, EarlyView.Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter +4 more
wiley +1 more source
A Set of Nonparametric Tests for Experiments with Lattice-Ordered Means: Theory, Programs, and Applications [PDF]
In many factorial experiments where the factors have levels that are ordinal or quantitative, a researcher may predict that the mean response in certain treatments will be higher or lower than those in other treatments.
Hsiao-Pin Liu +2 more
core +1 more source
The effect of caloric restriction on the forelimb skeletal muscle fibers of 1 the hypertrophic myostatin null mice [PDF]
, 2017 Skeletal muscle mass loss has a broad impact on body performance and physical activity. Muscle wasting occurs due to genetic mutation as in muscular dystrophy, age-related muscle loss (sarcopenia) as well as in chronic wasting disorders as in cancer ...
Arnhold, Stefan +4 more
core +2 more sources