Results 51 to 60 of about 33,582 (263)
Critical Care, 2022 Background The objective was to investigate the role of gene expression and plasma levels of the muscular protein myostatin in intensive care unit-acquired weakness (ICUAW).
Julius J. Grunow +12 more
doaj +1 more source
Myostatin dysfunction is associated with reduction in overload induced hypertrophy of soleus muscle in mice [PDF]
, 2017 Acknowledgements This project was also supported by Marie Curie International Reintegration Grant 249156 (A. Lionikas) and the grants VP1-3.1-SMM-01-V-02-003 (A. Kilikevicius) and MIP-067/2012 (T. Venckunas) from the Research Council of Lithuania as well
Alhindi, Y. +7 more
core +1 more source
Myostatin Levels and the Risk of Myopenia and Rheumatoid Cachexia in Women with Rheumatoid Arthritis
Journal of Immunological Research, 2022 Background. Myostatin is a regulator of muscle size. To date, there have been no published studies focusing on the relation between myostin levels and myopenia in rheumatoid arthritis (RA). Objective.
F. Gonzalez-Ponce +17 more
semanticscholar +1 more source
Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways. [PDF]
PLoS ONE, 2007 Myostatin is a transforming growth factor-beta family member that normally acts to limit skeletal muscle growth. Mice genetically engineered to lack myostatin activity have about twice the amount of muscle mass throughout the body, and similar effects ...
Se-Jin Lee
doaj +1 more source
Ammonia toxicity: from head to toe? [PDF]
, 2016 Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan +6 more
core +1 more source
Quadriceps myostatin expression in COPD [PDF]
European Respiratory Journal, 2010 To the Editors: Quadriceps muscle dysfunction is well recognised in chronic obstructive pulmonary disease (COPD), and is associated with impaired exercise capacity and increased mortality 1. Functionally, the quadriceps is characterised by reduced strength, increased fatigability and decreased endurance, associated with muscle fibre atrophy and a ...
W D-C, Man +6 more
openaire +2 more sources
npj Microgravity, 2023 Novel treatments for muscle wasting are of significant value to patients with disease states that result in muscle weakness, injury recovery after immobilization and bed rest, and for astronauts participating in long-duration spaceflight.
Andrea M. Hanson +6 more
doaj +1 more source
Generation of myostatin‐knockout chickens mediated by D10A‐Cas9 nickase
The FASEB Journal, 2020 Many studies have been conducted to improve economically important livestock traits such as feed efficiency and muscle growth. Genome editing technologies represent a major advancement for both basic research and agronomic biotechnology development.
Gap-Don Kim +7 more
semanticscholar +1 more source
Aging, 2014 The aging of a multicellular organism is an intricate process that results from signaling events and age-related degeneration in cells, tissues, and organ systems. Studies in model organisms have provided evidence of unanticipated connection between local and systemic aging [1]. Research in this field is defining the key tissues that govern an organism'
Vishal K, Patel, Fabio, Demontis
openaire +2 more sources
Frontiers in Immunology, 2017 Rheumatoid arthritis (RA) is characterized by the infiltration of a number of pro-inflammatory cytokines into synovial fluid and patients with RA often develop joint destruction and deficits in muscle mass.
Sung-Lin Hu +12 more
doaj +1 more source