Results 51 to 60 of about 26,633 (217)

Myostatin dysfunction is associated with reduction in overload induced hypertrophy of soleus muscle in mice [PDF]

, 2017
Acknowledgements This project was also supported by Marie Curie International Reintegration Grant 249156 (A. Lionikas) and the grants VP1-3.1-SMM-01-V-02-003 (A. Kilikevicius) and MIP-067/2012 (T. Venckunas) from the Research Council of Lithuania as well
Alhindi, Y., Baltusnikas, J., Bunger, L., Kilikevicius, A., Lionikas, A., Minderis, P., Ratkevicius, A., Venckunas, T.   +7 more
core   +1 more source

Association between serum GDF-15, myostatin, and sarcopenia in cardiovascular surgery patients

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Myostatin is a negative regulator of skeletal muscle mass. On the other hand, growth differentiation factor (GDF)-15 is associated with lower muscle strength and muscle mass.
Riichi Nishikawa, Taira Fukuda, Akiko Haruyama, Ikuko Shibasaki, Suomi Yamaguchi, Takuo Arikawa, Syotaro Obi, Hirohisa Amano, Hiroshi Yagi, Masashi Sakuma, Shichiro Abe, Hirotsugu Fukuda, Shigeru Toyoda, Toshiaki Nakajima   +13 more
doaj   +1 more source

Serum myostatin levels are associated with abdominal aortic calcification in dialysis patients

Kidney Research and Clinical Practice, 2019
Background : Serum myostatin levels are increased according to renal function decline and myostatin may be a main mediator of chronic kidney disease–related sarcopenia.
Su Mi Lee, Seong Eun Kim, Ji Young Lee, Hyo Jin Jeong, Young Ki Son, Won Suk An   +5 more
doaj   +1 more source

The central role of myostatin in skeletal muscle and whole body homeostasis [PDF]

, 2012
Myostatin is a powerful negative regulator of skeletal muscle mass in mammalian species. It plays a key role in skeletal muscle homeostasis and has now been well described since its discovery.
Allen, Allen, Amirouche, Amthor, Anker, Artaza, Artaza, Bakker, Bernard, Biga, Bish, Bodell, Bodine, Bogdanovich, Burgess, Cai, Castillero, Chen, Chen, Coffey, Costelli, Costelli, Dasarathy, Escobar, Feldman, Fernandez-Celemin, Franckhauser, Frost, Frost, Gentry, George, Goncalves, Gonzalez-Cadavid, Gonzalez-Cadavid, Gonzalez-Freire, Grobet, Gruson, Guo, Guttridge, Hayot, Heinemeier, Hill, Hill, Hirai, Hittel, Hosoyama, Hulmi, Jeanplong, Ji, Jiang, Jones, Kambadur, Kinouchi, Kirk, Kopple, Kraemer, Lang, Lang, Lang, Langen, Langen, Langley, Larsen, Larsen, Lawlor, Lee, Leger, Lehti, Li, Li, Li, Lin, Liu, Liu, Llovera, Lyons, Ma, Manini, Marcell, Mascher, Matsakas, Matsakas, Matzuk, McFarlane, McFarlane, McMahon, McMahon, McPherron, McPherron, McPherron, Megeney, Meienberg, Mendler, Milan, Mitch, Molina, Mosher, Murphy, Nakatani, Nicholas, Nozaki, Ohsawa, Oldham, Peters, Prontera, Ratkevicius, Reardon, Rebbapragada, Rios, Rodgers, Roth, Salehian, Schuelke, Schulte, Seibert, Sharma, Siriett, Southgate, Steffen, Stolz, Swallow, Taylor, Tessitore, Thies, Thomas, Wagner, Wagner, Walker, Weber, Whittemore, Willoughby, Willoughby, Yamaguchi, Yang, Yarasheski, Zachwieja, Zhang, Zhao, Zhu, Zimmers, Zurlo   +140 more
core   +1 more source

Systemic Problems: A perspective on stem cell aging and rejuvenation. [PDF]

, 2015
This review provides balanced analysis of the advances in systemic regulation of young and old tissue stem cells and suggests strategies for accelerating development of therapies to broadly combat age-related tissue degenerative pathologies.
CONBOY, Irina M, Conboy, Michael, Rebo, Justin   +2 more
core   +5 more sources

Skeletal muscle myopenia in mice model of bile duct ligation and carbon tetrachloride-induced liver cirrhosis [PDF]

, 2017
Skeletal muscle myopathy is universal in cirrhotic patients, however, little is known about the main mechanisms involved. The study aims to investigate skeletal muscle morphological, histological, and functional modifications in experimental models of ...
Ascenzi, Francesca, Barberi, Laura, Caporaso, Nicola, D'Argenio, Giuseppe, Di Sario, Francesca, Gaudio, Eugenio, Giusto, Michela, Merli, Manuela, Musaro', Antonio, Nicoletti, Carmine, Renzi, Anastasia, Rizzuto, Emanuele   +11 more
core   +1 more source

The C313Y Piedmontese mutation decreases myostatin covalent dimerisation and stability

BMC Research Notes, 2011
Background Myostatin is a key negative regulator of muscle growth and development, whose activity has important implications for the treatment of muscle wastage disorders.
Starck Carlene S, Sutherland-Smith Andrew J   +1 more
doaj   +1 more source

Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation

Advanced NanoBiomed Research, EarlyView.
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley   +1 more source

The Myostatin gene: an overview of mechanisms of action and its relevance to livestock animals [PDF]

, 2018
Myostatin, also known as Growth Differentiation Factor 8, a member of the Transforming Growth Factor-beta (TGF-β) super-family is a negative regulator of muscle development.
Amthor, Amthor, Barbaric, Baron, Bellinge, Beyer, Binns, Boman, Boman, Bouyer, Bower, Bryson-Richardson, Cappuccio, Casas, Cash, Chen, Clop, Dall'Olio, Dall'Olio, Dehnavi, Deng, Deveaux, Dunner, Elashry, Esmailizadeh, Fiems, Fontanesi, Georges, Girgenrath, Grisolia, Grobet, Gu, Hadjipavlou, Han, Hanset, Holmes, Hosoyama, Hu, Ji, Jiang, Kambadur, Kijas, Kobolák, Lach-Trifilieff, Langley, Latres, Leymaster, Li, Li, Liu, Lu, Marchitelli, Matsakas, McPherron, Miretti, Mirhoseini, Mosher, Nguluma, Omairi, Ouhayon, Petersen, Pothuraju, Qian, Qiao, Rudnicki, Sarti, Sazanov, Schuelke, Sellick, Sjakste, Stefaniuk, Stefaniuk, Sternstein, Stinckens, Thomas, Tozaki, Trendelenburg, Trukhachev, Vankan, Vincenti, Wang, Wang, Wegner, Wiener, Wolfman, Xu, Ye, Zhang, Zhang, Zhang, Zhao, Zhiliang, Zhou, Zou   +93 more
core   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK pathways

Arthritis &Rheumatology, Accepted Article.
Introduction Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source