Results 81 to 90 of about 1,038,892 (123)

Endosomal/Lysosomal Retention and Degradation of Major Histocompatibility Complex Class I Molecules Is Induced by Myxoma Virus [PDF]

, 1999
The highly immunosuppressive leporipoxvirus myxoma, previously was shown to promote the loss of cell surface class I major histocompatibility complex (MHC I) molecules.
Wang, Hong, McFadden, Grant, Barry, Michele, Zúñiga, Martha C.   +3 more
core   +1 more source

Effect of Myxoma Virus Species Jump on Iberian Hare Populations

Emerging Infectious Diseases
The myxoma virus species jump from European rabbits (Oryctolagus cuniculus) to Iberian hares (Lepus granatensis) has raised concerns. We assess the decline suffered by Iberian hare populations on the Iberian Peninsula and discuss the association between
Beatriz Cardoso, Ignacio García-Bocanegra, João Queirós, Javier Fernández-López, Paulo C. Alves, Pelayo Acevedo   +5 more
doaj   +1 more source

Interruption of cytokine networks by poxviruses: lessons from myxoma virus

, 1995
Myxoma virus is an infectious poxvirus pathogen that induces a virulent systemic disease called myxomatosis in European rabbits. The disease is rapidly and uniformly fatal to susceptible rabbits and is characterized by generalized dysfunction of cellular
Karen Mossman, Kathryn Graham, Joanne Macen, Michele Barry, Martha Schreiber, Piers Nash, Kimberly Ellison, Grant McFadden, Alshad Lalani, Helen Everett   +9 more
core   +1 more source

Identification and characterization of a novel non-structural protein of bluetongue virus [PDF]

, 2011
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins.
Rixon, F., Palmarini, M., Ratinier Maxime, Ratinier, Maxime, Golder, Matthew, Nunes, S.F., Alessia Armezzani, Sandro Filipe Nunes, Kathryn Allan, Allan Kathryn, Allan, K., Rixon, Frazer, Golder, M., Allan, Kathryn, Nunes Sandro Filipe, Frazer Rixon, Bayoumy, Amr, Shaw, A., Matthew Golder, Franzoni, G., Caporale Marco, Giulia Franzoni, Golder Matthew, Nunes, Sandro Filipe, Bayoumy Amr, Shaw, Andrew, Amr Bayoumy, Palmarini Massimo, Armezzani, A., Shaw Andrew, Palmarini, Massimo, Ratinier, M., Armezzani, Alessia, Franzoni Giulia, Franzoni, Giulia, Maxime Ratinier, Andrew Shaw, Rixon Frazer, Marco Caporale, Massimo Palmarini, Armezzani Alessia, Bayoumy, A., Caporale, Marco, Caporale, M.   +43 more
core   +1 more source

The Role of Myxoma Virus Immune Modulators and Host Range Factors in Pathogenesis and Species Leaping

Viruses
Myxoma virus (MYXV) is a leporipoxvirus that causes lethal disease in Leporids. Hares and rabbits belong to the Leporidae family and are believed to have had a common ancestor 12 million years ago.
Junior A. Enow, Ana M. Lopes, Joana Abrantes, Pedro J. Esteves, Masmudur M. Rahman   +4 more
doaj   +1 more source

Test Cases, Resolvability, and Group Selection: A Critical Examination of the Myxoma Case

, 2004
The evolution of the myxoma virus in Australia has been presented for many years as a test case for the hypothesis that group selection can function effectively ‘in the wild.’ This paper critically examines the myxoma case, and argues that its failure as
Wilson, Robert A.
core   +1 more source

Oncolytic Myxoma virus Increases Autophagy in Multiple Myeloma

Turkish Journal of Hematology
Objective: Multiple myeloma, which affects plasma cells, is the second most common hematological malignancy. Despite the development of new drugs and treatment protocols, patient survival has not reached the desired level.
Alpay Yeşilaltay, Dilek Muz, Berna Erdal   +2 more
doaj   +1 more source

Development and validation of a Myxoma virus real-time polymerase chain reaction assay [PDF]

, 2011
To aid in the rapid diagnosis of myxomatosis in rabbits, a real-time polymerase chain reaction (PCR) for the specific detection of Myxoma virus is described. Primers and probe were designed to amplify a 147-bp fragment within the Serp2 gene.
Sigrist, B, Regula Güttinger, Claude Schelling, Schelling, C, Andrea Vögtlin, Richard K. Hoop, Vogtlin, A, Sarah Albini, Guttinger, R, Hoop, R K, Brigitte Sigrist, Albini, S   +11 more
core   +1 more source

Poxvirus K3 Orthologs Regulate NF-κB-Dependent Inflammatory Responses by Targeting the PKR–eIF2α Axis in Multiple Species

Vaccines
Background: Protein kinase R (PKR) inhibits general mRNA translation by phosphorylating the alpha subunit of eukaryotic translation initiation factor 2 (eIF2).
Huibin Yu, Mary Eloise L. Fernandez, Chen Peng, Dewi Megawati, Greg Brennan, Loubna Tazi, Stefan Rothenburg   +6 more
doaj   +1 more source

Decrease in C-reactive protein levels in rabbits after vaccination with a live attenuated myxoma virus vaccine

Veterinární Medicína, 2016
The aim of this study was to evaluate the acute phase reaction and immune response of rabbits triggered by vaccination with a live attenuated myxoma virus (MXT) vaccine.
L. Ondruska, V. Parkanyi, J. Vasicek, R. Jurcik, E. Hanusova, D. Vasicek, A. Balazi, F. Vizzarri   +7 more
doaj   +1 more source