Results 91 to 100 of about 4,101 (195)

Humoral immune response to different routes of myxomatosis vaccine application

World Rabbit Science, 2018
The aim of our study was to monitor the dynamics of the serological response to different application routes of live attenuated myxomatosis vaccine. The study included 42 Californian breed rabbits, aged 3 mo, of both sexes.
I. Manev, K. Genova, A. Lavazza, L. Capucci   +3 more
doaj   +1 more source

Innate Immunity Never “NODs” Off: NLRs Regulate the Host Anti‐Viral Immune Response

Immunological Reviews, Volume 330, Issue 1, March 2025.
ABSTRACT A robust innate immune response is essential in combating viral pathogens. However, it is equally critical to quell overzealous immune signaling to limit collateral damage and enable inflammation resolution. Pattern recognition receptors are critical regulators of these processes.
Mackenzie K. Woolls, Madeline D. Mott, Cassandra S. Poole, Julia A. Gregory, Hannah M. Ivester, Irving Coy Allen   +5 more
wiley   +1 more source

Supplementary Figure S1 from Oncolytic Efficacy of Recombinant Vesicular Stomatitis Virus and Myxoma Virus in Experimental Models of Rhabdoid Tumors

, 2008
Supplementary Figure S1 from Oncolytic Efficacy of Recombinant Vesicular Stomatitis Virus and Myxoma Virus in Experimental Models of Rhabdoid ...
Hongyuan Zhou (3451382), Limei Wang (77943), Jaclyn A. Biegel (9335696), John W. Barrett (50504), Yushui Wu (14974159), Peter A. Forsyth (14881580), John C. Bell (206340), Grant McFadden (50513), Donna L. Senger (5693054), Xueqing Lun (77940), Beichen Sun (269122)   +10 more
core   +1 more source

Characterisation and Sensitivity of a Canine Mast Cell Tumour Line to Oncolytic Viruses

Veterinary and Comparative Oncology, Volume 23, Issue 1, Page 42-51, March 2025.
ABSTRACT Canine mast cell tumours (MCTs) are one of the most common skin cancers of dogs. Surgical removal is the primary treatment, but recurrence and metastasis can occur even with low‐grade tumours. As a result, new treatment strategies are being sought.
Yeganeh Mehrani, Julia E. Kakish, Christina Napoleoni, Jennifer Jane Thompson, Jason P. Knapp, Jessica A. Minott, Jacob G. E. Yates, Deirdre Stuart, Brenda L. Coomber, Robert A. Foster, Byram W. Bridle, Khalil Karimi   +11 more
wiley   +1 more source

Transformation of Fibroma into Myxoma Virus in Tissue Culture

Experimental Biology and Medicine, 1957
Summary1. Eleven experiments are described in which fibroma was transformed into myxoma virus in cultures of rabbit tissues, both of testes and of kidneys. 2. The transforming agent (TAM) was myxoma virus inactivated by heating at 65–67°C. 3. Live fibroma virus and TAM were inoculated into tissue cultures simultaneously and TAM was re-added at times of
openaire   +2 more sources

Partial sequencing of recent Portuguese myxoma virus field isolates exhibits a high degree of genetic stability [PDF]

, 2010
To study genetic changes underlying myxoma virus evolution in its new host, the European rabbit (Oryctolagus cuniculus), we sequenced selected genomic regions of nine recent virulent field strains and a live attenuated vaccine strain ("MAV", Germany ...
esteves, pj, P.J. Esteves, muller, a, N. Nowotny, abrantes, j, nowotny, n, E. Silva, A. Muller, carvalheira, jc, ferreira, pg, thompson, g, G. Thompson, J.C. Carvalheira, silva, e, P.G. Ferreira, J. Abrantes   +15 more
core   +1 more source

Construction and testing of a novel host-range defective myxoma virus vaccine with the M063 gene inactivated that is non-permissive for replication in rabbit cells [PDF]

, 2008
Deletion of the M063 gene from myxoma virus produces a virus that is unable to replicate in rabbit cells in vitro or in live rabbits but can be propagated in non-rabbit cell lines. A targeted M063 deletion mutant was constructed in the attenuated Uriarra
Barbara H. van Leeuwen, Adams, Mathew, Kerr, Peter, Mcfadden, Grant, Peter J. Kerr, van Leeuwen, Barbara, Mathew M. Adams, Grant McFadden   +7 more
core   +2 more sources

ISG15‐Dependent Stabilisation of USP18 Is Necessary but Not Sufficient to Regulate Type I Interferon Signalling in Humans

European Journal of Immunology, Volume 55, Issue 2, February 2025.
Antiviral interferon signalling requires tight regulation to prevent autoinflammation. In humans, ISG15 stabilises the negative regulator USP18. This study reveals that ISG15's role extends beyond stabilisation; its C‐terminal motif facilitates USP18's regulatory function by promoting higher affinity interactions, highlighting ISG15's broader impact on
Andri Vasou, Katie Nightingale, Vladimíra Cetkovská, Jonathan Scheler, Connor G. G. Bamford, Jelena Andrejeva, Jessica C. Rowe, Kirby N. Swatek, Ulrich Schwarz‐Linek, Richard E. Randall, John McLauchlan, Michael P. Weekes, Dusan Bogunovic, David J. Hughes   +13 more
wiley   +1 more source

A myxoma virus intergenic transient dominant selection vector

Journal of General Virology, 1992
The purpose of this study was to construct an intergenic transfer vector which can be used for the generation of recombinant myxoma viruses (MVs) expressing a foreign gene insert. Recombinant MVs expressing the Escherichia coli lacZ gene were constructed in vitro by transfection of MV-infected rabbit cells with a transfer expression vector, and ...
R J, Jackson, H G, Bults
openaire   +2 more sources

Expression of the Myxoma Virus Tumor Necrosis Factor Receptor Homologue and M11L Genes Is Required to Prevent Virus-Induced Apoptosis in Infected Rabbit T Lymphocytes

, 1996
Myxoma virus is a leporipoxvirus that causes a highly lethal virulent disease known as myxomatosis in the European rabbit. An important aspect of myxoma virus pathogenesis is the ability of the virus to productively infect lymphocytes and spread to ...
MACEN, JOANNE L., SCHREIBER, MARTHA, LEE, SIOW FONG, GRAHAM, KATHRYN A., MCFADDEN, GRANT, BOSHKOV, LYNN K.   +5 more
core   +1 more source