Results 111 to 120 of about 4,101 (195)

Characterisation of immunosuppression in rabbits after infection with myxoma virus

Veterinary Microbiology, 2008
Myxoma virus (MXV) causes the systemic disease myxomatosis in the European rabbit. Despite many in vitro studies on the function of MXV immunomodulatory proteins and detailed molecular knowledge of virus, little is known about the dynamics of interaction of the virus with the integrated host-immune system during infection.
Jeklova, Edita, Leva, Lenka, Matiasovic, Jan, Kovarcik, Kamil, Kudlackova, Hana, Nevorankova, Zora, Psikal, Ivan, Faldyna, Martin   +7 more
openaire   +3 more sources

Myxoma Virus M083 Is a Virulence Factor Which Mediates Systemic Dissemination

, 2018
Poxviruses are large, DNA viruses whose protein capsid is surrounded by one or more lipid envelopes. Embedded into these lipid envelopes are three conserved viral proteins which are thought to mediate binding of virions to target cells.
K. M. Dunlap, E. Bartee, A. M. Wolfe, M. Y. Bartee, A. C. Smith   +4 more
core   +1 more source

Histological differences at the primary myxoma site from rabbits infected by the Myxoma virus strains.

, 2015
NZW rabbits were inoculated with 100 PFUs of Myxoma virus WT, M138L Del, M138L STOP or M138L Rev strains in the left flank. A. Haematoxylin-eosin staining at day 4 p.i. B. Haematoxylin-eosin staining at day 9 p.i.
Bérengère Boutard (695119), Alain Vanderplasschen (33374), Nicolas Markine-Goriaynoff (695121), Laurent Gillet (31504), Daniel Desmecht (198345), Grant McFadden (50513), Sophie Vankerckhove (695120), Mickaël Sarlet (399173)   +7 more
core   +1 more source

Myxoma virus in rabbits : interaction with the immune system [PDF]

, 2017
Myxomaviruset är ett poxvirus, vars genom utgörs av ett dubbelsträngat DNA och replikation sker i cytoplasman hos infekterade celler. Viruset infekterar framför allt kaniner, men det finns indikationer på att även celler från andra arter kan infekteras ...
Trolin, Amanda
core  

Oclacitinib and Myxoma Virus Therapy in Dogs with High-Grade Soft Tissue Sarcoma. [PDF]

Biomedicines, 2023
Ashton LV, Weishaar KM, Séguin B, MacNeill AL.   +3 more
europepmc   +1 more source

Defects in intratumoral arginine metabolism attenuate the replication and therapeutic efficacy of oncolytic myxoma virus. [PDF]

J Immunother Cancer, 2023
Dryja P, Curtsinger HD, Bartee MY, Bartee E.   +3 more
europepmc   +1 more source

Virulence evolution of a salmonid virus following a host jump.

PLoS Pathogens
Emergent viral diseases remain a critical obstacle to welfare across landscapes and species, encompassing humans, wildlife, and agriculture. Following a jump to a novel host, the severity of disease resulting from infection is a critical determinant of ...
Malina M Loeher, Gael Kurath, David A Kennedy, Joanne E Salzer, William N Batts, Rachel B Breyta, Andrew R Wargo   +6 more
doaj   +1 more source

Oncolytic myxoma virus is effective in murine models of triple negative breast cancer despite poor rates of infection. [PDF]

Mol Ther Oncolytics, 2023
Thomas RJ, Bartee MY, Valenzuela-Cardenas M, Bartee E.   +3 more
europepmc   +1 more source

Selective Purging of Human Multiple Myeloma Cells from Autologous Stem Cell Transplantation Grafts using Oncolytic Myxoma Virus

, 2012
Autologous stem cell transplantation and novel therapies have improved overall survival of patients with multiple myeloma; however, most patients relapse and eventually succumb to their disease.
Cogle, Christopher R., McFadden, Grant, Moreb, Jan S., Bartee, Eric, Chan, Winnie M.   +4 more
core   +1 more source

Nuclear Export Inhibitor Selinexor Enhances Oncolytic Myxoma Virus Therapy against Cancer. [PDF]

Cancer Res Commun, 2023
Rahman MM, van Oosterom F, Enow JA, Hossain M, Gutierrez-Jensen AD, Cashen M, Everts A, Lowe K, Kilbourne J, Daggett-Vondras J, Karr TL, McFadden G.   +11 more
europepmc   +1 more source