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Myxoma Virus in Britain

Nature, 1955
IT is well known that myxomatosis has caused a high mortality among wild rabbit populations in most parts of England and Wales, and in those parts of Scotland and Ireland to which the disease has spread. Where it has been possible to make accurate observations, a mortality-rate of about 99 per cent was found. A similar death-rate was usual in Australia
J R, HUDSON, H V, THOMPSON, W, MANSI
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Immune Responses to Myxoma Virus

Viral Immunology, 2002
Myxoma virus causes the systemic disease myxomatosis in the European rabbit (Oryctolagus cuniculus). Originating in the South American rabbit Sylvilagus brasiliensis, where it causes a relatively localized fibroma, myxoma virus is a classic example of a virus that has jumped species to produce an exotic disease and then coevolved with its new host ...
Peter, Kerr, Grant, McFadden
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Electron Microscopy of Myxoma Virus

Nature, 1963
Ruska and Kausche1 and Farrant and Fenner2 demonstrated a close similarity, both in size and superficial morphology, between myxoma and vaccinia viruses. This, together with the demonstration of similarity in the pathogenesis of myxomatosis and other pox virus diseases, was considered by the latter authors to justify the inclusion of myxoma virus ...
P J, CHAPPLE, J C, WESTWOOD
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Immunomodulation by viruses: the myxoma virus story

Immunological Reviews, 1999
Summary: Myxoma virus is a poxvirus pathogen of rabbits that has evolved to replicate successfully in the presence of an active immune response by an infected host. To accomplish this, the virus has developed a variety of strategies to avoid detection by or obstruct specific aspects of the antiviral response whose consolidated action is antagonistic ...
P, Nash   +11 more
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Ultrastructural study of myxoma virus morphogenesis

Archives of Virology, 2006
Poxviruses are among the largest and most complex viruses known. Vaccinia virus, the prototype of the family Poxviridae, has been studied much more than myxoma virus. The aim of this work was to have a better knowledge about myxoma virus morphogenesis.
Duteyrat, Jl   +2 more
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Rapid purification of myxoma virus DNA

Journal of Virological Methods, 2009
A rapid and efficient procedure for the purification of myxoma virus DNA from infected cell cultures is described. The traditional method used for recovery of myxoma virus DNA involves multiple freeze-thawing cycles to disrupt cells and release virions followed by ultracentrifugation to concentrate virions for DNA extraction.
Kevin P, Dalton   +3 more
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The Fibroma-Myxoma Virus Transformation

1961
Publisher Summary This chapter relates how tissue culture, by enabling one to perform the transformation of fibroma into niyxonia virus in a predictable fashion, has opened up prospects of investigating the behavior of the deoxyribonucleic acids (DNA) of the viruses involved and their relation to processes of infection in mammalian host cells.
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Some aspects of the morphogenesis of myxoma virus in vivo

Archiv f�r die gesamte Virusforschung, 1972
The replication of myxoma virus was examined using thin sections of rabbit skin. The virus is assembled in the cytoplasm as crescent shaped structures which eventually form complete immature particles. These are roughly spherical, contain granular material and are limited by a unit membrane bearing spicules on its outer surface.
D A, Purcell, J K, Clarke
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Occurrence of Attenuated Strains of Myxoma Virus in Europe

Nature, 1955
SEVERAL slightly attenuated strains of myxoma virus have been recovered from the field in Australia1; indeed, it is now rather uncommon to recover strains having the same high virulence as the material used for initiating the epizootics, and for the subsequent inoculation campaigns.
F, FENNER, I D, MARSHALL
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A MYXOMA VIRUS EPIZOOTIC IN A BRUSH RABBIT POPULATION

Journal of Wildlife Diseases, 1972
During the spring and summer months of 1964 more than 95% of a population of brush rabbits (Sylrilagus bachmani) became infected with Californian myxoma virus. The characteristics of the epizootic and its effect on this species reinforce the assumption that the brush rabbit is an endemic reservoir of the Californian myxoma virus.
D C, Regnery, J H, Miller
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