Results 41 to 50 of about 13,560,164 (207)

Para-psychology, N, N-dimethyltryptamine and the pineal gland [PDF]

, 2018
In the last decades, one of the psychedelic substances which has gained high attention for its implications in several para-psychological phenomena (including out-of-body states, deep changes in sensory perception, mood, and thought, travels in ...
Firenzuoli F., Penazzi G., Khabbache H., Bragazzi N. L., M. j Zerbetto, T. S., Simões, Neri B., Perduca M., R. Re   +9 more
core  

Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study

Addiction, EarlyView.
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock, Krista J. Siefried, Gill Bedi, Steven Albert, Richard O. Day, Nadine Ezard, Margaret Ross, Paul Liknaitzky, Jonathan Brett   +8 more
wiley   +1 more source

A SYSTEMATIC REVIEW OF RESEARCH ON N,N-DIMETHYLTRYPTAMINE

, 2017
Introduction: The effects of the endogenous hallucinogen N,N-dimethyltryptamine are poorly understood and its medical significance is widely unknown. A small number of  studies regarding its biochemical, pharmaceutical and physiological role have been ...
Hristova, Denitsa, Zhelyazkova-Savova, Maria   +1 more
core   +1 more source

Prospective examination of synthetic 5-methoxy-N,N-dimethyltryptamine inhalation:effects on salivary IL-6, cortisol levels, affect, and non-judgment

, 2020
RATIONALE: 5-methoxy-N,N-dimethyltryptamine is a psychotropic substance found in various plant and animal species and is synthetically produced. 5-methoxy-N,N-dimethyltryptamine is used in naturalistic settings for spiritual exploration, recreation, or ...
Davis, Alan K, Uthaug, Malin V., Riba, Jordi, Szabo, Attila, Ramaekers, Johannes G., Lancelotta, Rafael   +5 more
core   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Effects of hallucinogenic drugs on the human heart

Frontiers in Pharmacology
Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin receptors, namely, 5-HT2A-serotonin receptors in the brain.
Joachim Neumann, Stefan Dhein, Uwe Kirchhefer, Britt Hofmann, Ulrich Gergs   +4 more
doaj   +1 more source

Psychological change processes in alcohol use disorder: A qualitative study of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) with cognitive behavioural therapy

Addiction, EarlyView.
Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, James J. Rucker, Anthony Cleare, John Marsden   +6 more
wiley   +1 more source

Effects of N,N-dimethyltryptamine on electrically evoked responses in the cat visual system and modification by neuroleptic agents, [PDF]

, 1976
The effects of N,N-dimethyltryptamine on electrically evoked potentials in the visual system of the cat and the interaction of selected neuroleptic agents with dimethyltryptamine were studied.
Moore, R. H., Hatada, K., Domino, Edward F.   +2 more
core   +1 more source

sj-docx-1-jop-10.1177_02698811221104054 – Supplemental material for Significance of mammalian N, N-dimethyltryptamine (DMT): A 60-year-old debate

, 2022
Supplemental material, sj-docx-1-jop-10.1177_02698811221104054 for Significance of mammalian N, N-dimethyltryptamine (DMT): A 60-year-old debate by Javier Hidalgo Jiménez and José Carlos Bouso in Journal of ...
Javier Hidalgo Jiménez (12876833), José Carlos Bouso (10680081)   +1 more
core   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source