Results 71 to 80 of about 4,502 (185)
Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?
British Journal of Pharmacology, EarlyView.Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi +10 more
wiley +1 more source
Psychological variables implied in the therapeutic effect of ayahuasca: A contextual approach [PDF]
, 2018 Ayahuasca is a psychedelic decoction originating from Amazonia. The ayahuasca-induced introspective experience has been shown to have potential benefits in the treatment of several pathologies, to protect mental health and to improve neuropsychological ...
Alcázar Córcoles, Miguel Ángel +5 more
core +1 more source
British Journal of Pharmacology, EarlyView.Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller +3 more
wiley +1 more source
Complexity and connectivity markers for N,N-dimethyltryptamine (DMT) [PDF]
N, N-Dimethyltryptamine (DMT) is a substance used in indigenous rituals. This psychedelic drug has attracted recent interest for its potential in psychotherapy, yet its effects on the brain remain unclear. The main objective of this project is to analyze through various biomarkers, how the brain functions in altered states of consciousness, such as ...
Araujo Rodríguez, Helena María
core +5 more sources
Pharmaceuticals, 2020 Ayahuasca is a hallucinogenic botanical beverage originally used by indigenous Amazonian tribes in religious ceremonies and therapeutic practices. While ethnobotanical surveys still indicate its spiritual and medicinal uses, consumption of ayahuasca has ...
Andreia Machado Brito-da-Costa +4 more
doaj +1 more source
New drugs on the Internet : the case of Camfetamine [PDF]
, 2014 Copyright © 2014 Eduardo Cinosi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly ...
Acciavatti, Tiziano +6 more
core +3 more sources
Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, EarlyView.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research
Mass Spectrometry Reviews, Volume 45, Issue 2, Page 429-452, March/April 2026.ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke +3 more
wiley +1 more source
Examining changes in personality following shamanic ceremonial use of ayahuasca
Scientific Reports, 2021 The present study examines the association between the ceremonial use of ayahuasca—a decoction combining the Banistereopsis caapi vine and N,N-Dimethyltryptamine-containing plants—and changes in personality traits as conceived by the Five-Factor model ...
Brandon Weiss +3 more
doaj +1 more source
Pharmacological MRI: Utility in Understanding Drug Mechanisms in Psychiatric Disorders
Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 346-363, February 2026.ABSTRACT Pharmacological MRI (pharmaMRI) has emerged as a powerful tool to study how psychoactive drugs affect brain function and to uncover mechanisms of drug action in psychiatric disorders. This review provides an overview of key techniques used in pharmaMRI, including BOLD‐fMRI, arterial spin labeling (ASL), and cerebral blood volume (CBV) mapping,
Christin Y. Sander +4 more
wiley +1 more source