Results 51 to 60 of about 559,078 (257)

Amiloride hydro­chloride methanol disolvate [PDF]

, 2010
In the crystal of the title compound [systematic name: 2-(3,5-diamino-6-chloro­pyrazin-2-ylcarbon­yl)guanidinium chloride methanol disolvate], C6H9ClN7O+·Cl-·2CH3OH , the components are connected by N—H ... N, N—H ... Cl, N—H ... O, O—H ...
Bolte, Michael, Cuong, Ton Quoc
core  

5-Bromo­pyrimidin-2(1H)-one [PDF]

, 2007
The geometric parameters of the title compound, C4H3BrN2O, are in the usual ranges.
Ashalatha, B. V., Bolte, Michael, Narayana, B., Sarojini, B. K., Yathirajan, H. S.   +4 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Pyrimidin-2-amine–1-phenylcyclopentane-1-carboxylic acid (1/1)

Acta Crystallographica Section E, 2011
In the crystal structure of the title co-crystal, C4H5N3·C12H14O2, the components are linked by N—H...O and O—H...N hydrogen bonds.
Guangwen He, Srinivasulu Aitipamula, Pui Shan Chow, Reginald B. H. Tan   +3 more
doaj   +1 more source

Investigation of the crystal structures of n-(4-fluorobenzoyl) benzenesulfonamide and n-(4-fluoro-benzoyl)-4-methylbenzenesulfonamide [PDF]

, 1977
The title compound, C26H26N2O7, is a thia­midine derivative. Geometric parameters are in the usual ranges. The crystal packing is stabilized by a classical N—H⋯O hydrogen bond, several weak C—H⋯O hydrogen bonds and a π–π stacking inter ...
Suchetan, P. A., Sreenivasa, Swamy, Srivishnu, K. S., Lakshmikantha, H. N., Supriya, G. M., Naveen, S., Lokanath, N. K.   +6 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

4-Amino-2-hydroxybenzohydrazide

Acta Crystallographica Section E, 2012
The asymmetric unit of the title compound, C7H9N3O2, comprises two crystallographically independent molecules (A and B). In each molecule there is an intramolecular O—H...O hydrogen bond making an S(6) ring motif.
Hadi Kargar, Reza Kia, Muhammad Nawaz Tahir   +2 more
doaj   +1 more source

9-Aminoacridin-10-ium 4-aminobenzoate dihydrate [PDF]

, 2014
The asymmetric unit of the title hydrated salt, C13H11N2 +.-C7H6NO2-.2H2O, consists of two independent 9-aminoacridinium cations, two 4-aminobenzoate anions and four water molecules.
Arshad, Suhana, Dhanabalan, Nallathambi, Razak, Ibrahim Abdul, Santhanaraj, K. Joseph, Thanigaimani, Kaliyaperumal   +4 more
core   +3 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1)

Acta Crystallographica Section E, 2008
In the title cocrystal, C6H9N3O2·C7H7NO2, the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimethoxy pyrimidine-anthranilic acid adducts.
Kaliyaperumal Thanigaimani, Packianathan Thomas Muthiah, Daniel E. Lynch   +2 more
doaj   +1 more source