Results 61 to 70 of about 269,935 (266)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

[(5-Bromo-1H-indol-3-yl)methyl]dimethylazanium nitrate

Acta Crystallographica Section E, 2011
In the title compound, C11H14BrN2+·NO3−, intermolecular N—H...O and N—H...N hydrogen bonds link the protonated 5-bromogramine cation and the nitrate anions.
Qing Wang, Zhong-Ye Fu, Xia Li, Liang-Min Yu   +3 more
doaj   +1 more source

Crystal structure and Hirshfeld surface analysis of ethyl (3E)-5-(4-fluorophenyl)3-{[(4-methoxyphenyl)formamido]imino}-7-methyl-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate 0.25-hydrate

Acta Crystallographica Section E: Crystallographic Communications, 2022
In the title compound, C24H23FN4O4S·0.25H2O, the dihydropyrimidine ring is distinctly non-planar, with the flap C atom deviating by 0.297 (2) Å from the least-squares plane.
Shaaban K. Mohamed, Joel T. Mague, Mehmet Akkurt, Abdallah M. Alfayomy, Fatma A. F. Ragab, Mokhtar A. Abd ul-Malik   +5 more
doaj   +1 more source

Cation–Cation Pairing by N-C-H···O Hydrogen Bonds [PDF]

, 2015
The pairing of ions of opposite charge is a fundamental principle in chemistry, and is widely applied in synthesis and catalysis. In contrast, cation–cation association remains an elusive concept, lacking in supporting experimental evidence.
Gamrad, W., Dreier, A., Goddard, R., Pörschke, K.   +3 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Crystal structures of 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(naphthalen-1-yl)acetamide and 2-[(4,6-diaminopyrimidin-2-yl)sulfanyl]-N-(4-fluorophenyl)acetamide

Acta Crystallographica Section E: Crystallographic Communications, 2017
The title compounds, C16H15N5OS, (I), and C12H12FN5OS, (II), are [(diaminopyrimidine)sulfanyl]acetamide derivatives. In (I), the pyrimidine ring is inclined to the naphthalene ring system by 55.5 (1)°, while in (II), the pyrimidine ring is inclined to ...
S. Subasri, Timiri Ajay Kumar, Barij Nayan Sinha, Venkatesan Jayaprakash, Vijayan Viswanathan, Devadasan Velmurugan   +5 more
doaj   +1 more source

2,2′-(1-Phenyl-1H-pyrazole-3,5-di­yl)diphenol [PDF]

, 2009
The title compound, C21H16N2O2, was derived from 1-(2-hydroxyphenyl)-3-(-methoxyphenyl)propane-1,3-dione. The molecular structure of the title compound is stabilized by an intramolecular O-H...N hydrogen bond. The dihedral angle between the hydroxyphenyl
Bolte, Michael, Aurangzeb Hasan, Badshah, Amir, Michael Bolte, Ikram, Sumeera, Hasan, Aurangzeb, Amir Badshah, Zia ul Haq, Muhammad, Muhammad Zia ul Haq, Sumeera Ikram   +9 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Crystal Engineering with ⋮C−H···N and C−H···N Hydrogen Bonds [PDF]

, 2016
Ethynylpyridines show straight and zigzag chain patterns formed by ⋮C−H···N hydrogen bonds; cross-stitching of zigzag chains by C−H···N hydrogen bonds leads to two-dimensional networks with predictable topology in 5 ...
Marta Dabros (1429852), Hans-Christoph Weiss (2125642), Annette Gehrke (2497618), Roland Boese (1515988), Venkat R. Thalladi (2497615)   +4 more
core   +3 more sources

Crystal structure of 1-(2,4-dimethylphenyl)urea

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title urea derivative, C9H12N2O, the dihedral angle between the benzene ring and the mean plane of the urea group, N—C(=O)—N, is 86.6 (1)°. In the crystal, the urea O atom is involved in three N—H...O hydrogen bonds. Molecules are linked via pairs
L. Jayalakshmi, C. Ramalingan, B. Sridhar, S. Selvanayagam   +3 more
doaj   +1 more source