Results 111 to 120 of about 14,619 (195)

In vivo neurometabolic profiling in orthostatic tremor [PDF]

, 2016
The pathogenesis of orthostatic tremor (OT) remains unclear, although some evidence points to dysfunction in the brainstem or cerebellum. We used single voxel proton magnetic resonance spectroscopy (1H-MRS) (3 T) to investigate whether neurochemical ...
Benito-León, Julián, Dydak, Ulrike, Hernández-Tamames, Juan Antonio, Louis, Elan D., Malpica, Norberto, Matarazzo, Michele, Mato-Abad, Virginia, Molina-Arjona, José Antonio, Romero, Juan Pablo, Sánchez-Ferro, Álvaro, Álvarez-Linera, Juan   +10 more
core   +2 more sources

Carbamazepine treatment recovered low N-acetylaspartate+N-acetylaspartylglutamate (tNAA) levels in the megencephaly mouse BALB/cByJ-Kv1.1mceph/mceph

Neurobiology of Disease, 2007
Megencephaly mice (BALB/cByJ-Kv1.1mceph/mceph) display excessive brain growth and seizures related to a mutation within the potassium channel gene Kv1.1 producing a malfunctioning protein.
Eric Westman, Christian Spenger, Lars-Olof Wahlund, Catharina Lavebratt   +3 more
doaj   +1 more source

Metabolite alterations in the　hippocampus of high-functioning adult subjects with autism [PDF]

, 2009
The aim of the present study was to investigate metabolite alterations in the hippocampal formation as they relate to aggression in high-functioning adults with autism.
Isoda, Haruo, Matsumoto, Kaori, Mori, Norio, Nakamura, Kazuhiko, Nishimura, Katsuhiko, Sakahara, Harumi, Sugihara, Genichi, Sugiyama, Toshiro, Suzuki, Katsuaki, Takebayashi, Kiyokazu, Takei, Nori, Tsuchiya, Kenji J., Tsujii, Masatsugu   +12 more
core   +2 more sources

Cigarette smoking is associated with amplified age-related volume loss in subcortical brain regions [PDF]

, 2017
BACKGROUND: Magnetic resonance imaging studies of cigarette smoking-related effects on human brain structure have primarily employed voxel-based morphometry, and the most consistently reported finding was smaller volumes or lower density in anterior ...
Durazzo, Timothy C., Meyerhoff, Dieter J., Murray, Donna E., Yoder, Karmen K.   +3 more
core   +1 more source

Hippocampal region metabolites and cognitive impairment in patients with general paresis: based on 1H-proton magnetic resonance spectroscopy

Frontiers in Pharmacology
Background:This study utilizes Hydrogen proton magnetic resonance spectroscopy (1H-MRS) to investigate metabolite concentrations in the bilateral hippocampus of general paresis (GP) patients.Methods:A total of 80 GP patients and 57 normal controls (NCs ...
Xin Che, Xin Che, Xin Che, Tianyang Miao, Tianyang Miao, Tianyang Miao, Haishan Shi, Haishan Shi, Haishan Shi, Zezhi Li, Zezhi Li, Zezhi Li, Yuping Ning, Yuping Ning, Yuping Ning   +14 more
doaj   +1 more source

Lactate, N-acetylaspartate, choline and creatine concentrations, and spin-spin relaxation in thalamic and occipito-parietal regions of developing human brain [PDF]

, 1996
Previous studies of the brains of normal infants demonstrated lower lactate (Lac)/choline (Cho), Lac/creatine (Cr), and Lac/ N-acetylaspartate (Naa) peak-area ratios in the thalamic region (predominantly gray matter) compared with occipitoparietal ...
A. Lorek, E.B. Cady, E.O. Reynolds, F. Franconi, J. Penrice, J.S. Wyatt, M. Wylezinska, P.N. Amess, R.F. Aldridge   +8 more
core   +1 more source

Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS [PDF]

, 2012
Despite significant progress in the development of therapies for relapsing MS, progressive MS remains comparatively disappointing. Our objective, in this paper, is to review the current challenges in developing therapies for progressive MS and identify ...
Baker, D, Baneke, P, Brown, D, Browne, P, Chandraratna, D, Ciccarelli, O, Coetzee, T, Comi, G, Feinstein, A, Fox, RJ, Kapoor, R, Lee, K, Salvetti, M, Sharrock, K, Thompson, A, Toosy, A, Zaratin, P, Zuidwijk, K   +17 more
core   +2 more sources

N-acetylaspartic acid monitors oxidative stress

, 2011
EXCLI Journal ; Vol.
openaire   +2 more sources

Hypothermia for encephalopathy in low and middle-income countries (HELIX): Study protocol for a randomised controlled trial [PDF]

, 2017
BACKGROUND: Therapeutic hypothermia reduces death and disability after moderate or severe neonatal encephalopathy in high-income countries and is used as standard therapy in these settings.
Atreja, G, Babu, M, Bandya, P, Bassett, P, Benkappa, N, Bhiskar, S, Chandramohan, R, Chandrasekaran, M, Chathirangika, K, Dewang, K, Dey, AC, Dey, SK, Herberg, J, Islam, MN, Islam, MT, Jahan, I, Jain, A, Kamalaratnam, C, Kantharajanna, U, Karunaratne, R, Karunasagar, I, Klein, N, Krishnappa, S, Kumaran, S, Kumaraswami, K, Lally, PJ, Madhavan, V, Manerkar, S, Mangalabharathi, S, Mankad, K, Mannan, MA, Mendoza, J, Mondkar, J, Moni, SC, Montaldo, P, Munasinghe, S, Nahar, MN, Nair, M, Natarajan, K, Oliveira, V, Prakash, V, Rajindrajith, S, Ramji, S, Rodrigo, R, Rohit, A, Sajjid, M, Sathyanathan, BP, Sebastian, M, Sebire, N, Seeralar, A, Shabuj, KH, Shahidullah, M, Shankaran, S, Shivanna, NH, Somanna, J, Sumanasena, S, Swamy, R, Thayyil, S, Vadekepad, P, Wanigasinghe, J   +59 more
core   +1 more source

Proton Magnetic Resonance Spectroscopy in Patients with Migration Disorders [PDF]

, 1999
Proton Magnetic Resonance Spectroscopy (1H-MRS) can be used to detect cerebral metabolites including N-acetylaspartate (NAA)，creatine (Cr) and choline (Ch). Hence，clinical applications of this method for neuropediatric diseases can be expected.
Asano, Takashi, Hiraki, Norio, Kawahara, Michiko, Ohtahara, Shunsuke, Oka, Eiji, Sakae, Katsumi, Sanada, Satoshi   +6 more
core   +1 more source