Results 91 to 100 of about 47,831 (279)
Advanced Science, EarlyView.Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang +11 more
wiley +1 more source
N‐acetylcysteine microparticles reduce cisplatin‐induced RSC96 Schwann cell toxicity
Laryngoscope Investigative OtolaryngologyObjectives Cisplatin is known to cause inner ear dysfunction. There is growing evidence that cisplatin‐induced demyelination of spiral or Scarpa's ganglion neurons may play an additional role in drug‐induced ototoxicity alongside afferent neuron injury ...
Katherine Kedeshian +3 more
doaj +1 more source
Correction to: N acetylcysteine in the treatment of alcohol use disorder: a randomized, double-blind, placebo-controlled trial [PDF]
, 2023 openalex +1 more source
Advanced Science, EarlyView.Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source
AntioxidantsAlbumin (HSA) is the most abundant circulating protein and plays a pivotal role in maintaining the redox state of the plasma. Three HSA proteoforms have been identified based on the redox state of cysteine 34.
Sonia Eligini +4 more
doaj +1 more source
BMEMat, EarlyView.Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin +17 more
wiley +1 more source
Effect of inhaled and oral n-acetylcysteine on airway defense mechanism
European Pharmaceutical Journal, 2017 Aim: N-acetylcysteine is the prototype of mucolytic agents. The aim of this study was to evaluate the acute and chronic effect of inhaled and oral N-acetylcysteine on airway reactivity, cough reflex and ciliary beat frequency and parameters of mentioned ...
Pappová L. +2 more
doaj +1 more source
ChemMedChem, EarlyView.Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto +12 more
wiley +1 more source
Considerations for drug trials in hypertrophic cardiomyopathy
ESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant +17 more
wiley +1 more source