Results 151 to 160 of about 44,243 (239)

Repression of Virulence in Staphylococcus aureus by 2‐Aminothiol‐Mediated Quorum Quenching

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Simple analogues of cysteine that can eliminate the native autoinducing peptides (AIPs) of staphylococci extracellularly, before they activate their receptor, and turn off quorum sensing in different Staphylococcus aureus. The elimination of AIPs occurs through a mechanism similar to native chemical ligation (NCL). Further, this strategy showed promise
Bengt H. Gless, Riccardo Milazzo, Martin S. Bojer, Benjamin S. Sereika‐Bejder, Hanne Ingmer, Christian A. Olsen   +5 more
wiley   +2 more sources

Unraveling the complex role of intestinal microbiota in drug permeability: Insights from N-acetylcysteine. [PDF]

Asian J Pharm Sci
Tian C, He Z.
europepmc   +1 more source

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

European Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman, Sreya Rahman, Francesca Polverino, Muhammad Adrish   +3 more
wiley   +1 more source

N-acetylcysteine: evidence based consensus document on the therapeutic advantages in respiratory diseases (NECTAR). [PDF]

Front Med (Lausanne)
Barne M, Shevade M, Bhattacharyya P, Christopher DJ, Nair S, Abhyankar N, Halder I, Vora A, Khanna A, Swarnakar R, Chhajed P, Santhalingam B, Nair A, Salvi S.   +13 more
europepmc   +1 more source

Ya‐Jie‐Sha‐Ba Decoction Regulates Arachidonic Acid Metabolism to Treat Alcohol‐Associated Liver Disease by Activating PPARα–CYP4A14 Axis: Insights From Multi‐Omics Analysis and Experimental Validations

Journal of Cellular and Molecular Medicine, Volume 30, Issue 19, October 2026.
ABSTRACT Ya‐Jie‐Sha‐Ba decoction (YJSB), a traditional Dai medicinal formulation, has been widely used by the Dai ethnic group and has shown efficacy in alleviating alcohol‐associated liver disease (ALD). However, the molecular mechanism of YJSB in the management of ALD remains unclear.
Dehong Ma, Xia Chen, Huixian Dao, Hongyu Deng, Yingcheng Guo, Hui Yang, Yuanyuan Chen, Congmei Zhang, Yuan Long, Weibo Wen, Yinghong Zhao, Huantian Cui   +11 more
wiley   +1 more source

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

Veterinary Dermatology, Volume 37, Issue 5, Page 581-591, October 2026.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro, Emma R. Bollig, Jennifer L. Granick   +2 more
wiley   +1 more source

N-acetylcysteine mitigates oxidative stress and reduces alveolar bone damage on experimental periodontitis in rats. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Silva APA, Dos Santos EA, Frazão DR, Dos Santos VRN, Matos-Sousa JM, Peinado BR, Souza-Monteiro D, Melo WWP, da Silva ZA, Varela ELP, da Cruz JN, da Silva-Boghossian CM, Collares FM, de Souza-Rodrigues RD, Lima RR.   +14 more
europepmc   +1 more source

N-Acetylcysteine Therapy in Thrombotic Thrombocytopenic Purpura: A Systematic Review and Critical Appraisal. [PDF]

J Clin Med
Demirci U, Bilgin ZT, Baysal M.
europepmc   +1 more source

N-acetylcysteine modulates neutrophil-driven immune and metabolic pathways in steatotic liver ischemia-reperfusion injury. [PDF]

Front Immunol
Kang J, Patil D, Hackett R, Cui Y, Oza K, Rutkowski A, Liggett JR, Li H, Ranjit S, Kwon D, Kallakury B, Albanese C, Gondolesi GE, Ekong U, Cui W, Khan K, Fishbein TM, Kroemer A.   +17 more
europepmc   +1 more source