Results 71 to 80 of about 14,739 (167)

Plasma Pharmacokinetics of N-Acetylgalactosamine-Conjugated Small-Interfering Ribonucleic Acids (GalNAc-Conjugated siRNAs). [PDF]

Clin Pharmacokinet, 2023
Sten S, Cardilin T, Antonsson M, Gennemark P.   +3 more
europepmc   +1 more source

Targeted and synergistic therapy for hepatocellular carcinoma: monosaccharide modified lipid nanoparticles for the co-delivery of doxorubicin and sorafenib

Drug Design, Development and Therapy, 2018
Wendu Duan, Yan Liu Department of Hepatobiliary Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei Province 071000, People’s Republic of China Purpose: Targeted hepatocellular carcinoma therapy was carried out to improve the ...
Duan W, Liu Y
doaj  

Multivalent Lactobionic Acid and N-Acetylgalactosamine-Conjugated Peptide Nucleic Acids for Efficient In Vivo Targeting of Hepatocytes. [PDF]

Adv Healthc Mater, 2023
Kumar V, Wahane A, Gupta A, Manautou JE, Bahal R.   +4 more
europepmc   +1 more source

Increased Cerebral Serum Amyloid A2 and Parameters of Oxidation in Arylsulfatase B (N-Acetylgalactosamine-4-Sulfatase)-Null Mice. [PDF]

J Alzheimers Dis Rep, 2023
Bhattacharyya S, Tobacman JK.
europepmc   +1 more source

Yeast Expression and Enzymatic Characterization of a Novel N-Acetylgalactosamine Transferase from Apus apus

Shipin gongye ke-ji
In this study, a novel N-acetylgalactosaminyltransferase (GalNAcT) was developed for in vitro modification of mucins by O-glycosylation. A recombinant expression vector containing the ppGalNAcT gene derived from the common swift (Apus apus ...
Chencheng HONG, Zixuan HU, VOGLMEIR Josef, Li LIU   +3 more
doaj   +1 more source

N-glycan antennal modifications are altered in Caenorhabditis elegans lacking the HEX-4 N-acetylgalactosamine-specific hexosaminidase. [PDF]

J Biol Chem, 2023
Paschinger K, Wöls F, Yan S, Jin C, Vanbeselaere J, Dutkiewicz Z, Arcalis E, Malzl D, Wilson IBH.   +8 more
europepmc   +1 more source

The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine. [PDF]

Commun Biol, 2022
Le Mauff F, Razvi E, Reichhardt C, Sivarajah P, Parsek MR, Howell PL, Sheppard DC.   +6 more
europepmc   +1 more source

Targeting Angiotensinogen With N-Acetylgalactosamine-Conjugated Small Interfering RNA to Reduce Blood Pressure. [PDF]

Arterioscler Thromb Vasc Biol, 2023
Ye D, Cruz-López EO, Tu HC, Zlatev I, Danser AHJ.   +4 more
europepmc   +1 more source

The N-Acetylgalactosamine-conjugated small interfering RNA inclisiran can be coadministered safely with atorvastatin in cynomolgus monkeys resulting in additive low-density lipoprotein cholesterol reductions. [PDF]

Pharmacol Res Perspect, 2023
Lehoux D, Kallend D, Wijngaard PLJ, Brown AP, Zerler B.   +4 more
europepmc   +1 more source

Author Correction: The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine. [PDF]

Commun Biol, 2022
Le Mauff F, Razvi E, Reichhardt C, Sivarajah P, Parsek MR, Howell PL, Sheppard DC.   +6 more
europepmc   +1 more source