Circannual pattern and Temperature-related incidence of Electrical Storm: the Tempest study [PDF]
, 2017 Introduzione Electrical storm (ES) è definite come la presenza di 3 o più episodi di tachycardia ventricolare sostenuta (VT) o fibrillazione ventricolare (VF) in 24 ore che richiede o pacing anti tachicardico (ATP) o cardioversione/defibrillazione. Le
CIPOLLETTA, LAURA
core
S,S,S-Tris(2-ethylhexyl) phosphorotrithioate as an effective solvent mediator for a mexiletine-sensitive membrane electrode [PDF]
, 2007 S,S,S-Tris(2-ethylhexyl) phosphorotrithioate proved to be an effective solvent mediator for constructing a mexiletine-sensitive membrane electrode in combination with an ion-exchanger, sodium tetrakis[3,5-bis(2-methoxyhexafluoro-2-propyl)phenyl]borate ...
Hanioka, Nobumitsu +5 more
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Pharmacodynamics of intravenous procainamide as used during acute electropharmacologic testing [PDF]
, 1988 No previous studies have determined the pharmacodynamics of intravenous procainamide when administered in a dose of 15 mg/kg and at a rate of 50 mg/min, as is common practice during etectropharmacologic testing.
Annesley, Thomas M. +6 more
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A Correlation between Protein Function and Ligand Binding Profiles [PDF]
, 2011 We report that proteins with the same function bind the same set of small molecules from a standardized chemical library. This observation led to a quantifiable and rapidly adaptable method for protein functional analysis using experimentally-derived ...
Bokemper, Michael +4 more
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PHARMACOKINETIC DRUG-DRUG INTERACTIONS MEDIATED BY ORGANIC CATION TRANSPORTERS: ARE ANTIMALARIAL DRUGS SIGNIFICANTLY AFFECTED? [PDF]
A clear understanding of all the processes that influence drug disposition is important to enable a prediction of pharmacokinetic drug interactions.
ONYEJI, Cyprian Ogbonna
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, 1983 dissertationQuinidine is a naturally occurring substance used in the treatment of cardiac arrhythmias. It may be administered orally or parenterally to control both ventricular and supraventricular arrhythmias. Because of its low therapeutic index, it is
Gonzalez, Edgar R.
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Pharmacogenetic studies on the drug-related lupus syndrome. differences in antinuclear antibody development and drug-induced DNA damage in rapid and slow acetylator animal models [PDF]
, 1981 Pharmacogenetic study of an inbred mouse model system derived from A/J (slow acetylator) and C57BL/6J (rapid acetylator) parental strains shows that spontaneous occurrence of antinuclear antibodies is associated with the slow acetylator phenotype ...
Brown +40 more
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Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus [PDF]
, 2002 Objective Inhibition of T cell DNA methylation causes autoreactivity in vitro and a lupus-like disease in vivo, suggesting that T cell DNA hypomethylation may contribute to autoimmunity. The hypomethylation effects are due, in part, to overexpression of
Arnett +32 more
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Circadian changes in procainamide and N-acetylprocainamide kinetics in the rat
Journal of Pharmacy and Pharmacology, 1985 AbstractThe aim of this study was to investigate the possible influence of the time of administration on procainamide and N-acetylprocainamide (NAPA) kinetics in the rat. A single 50 mg kg−1 i.p. dose of procainamide was given to Wistar AF SPF adult male rats maintained under controlled environmental conditions (LD: 06.00h-18.00h) at four different ...
B, Bruguerolle, G, Jadot
openaire +2 more sources
Target Molecules for Reactive Free Radical Metabolites of Aromatic Amines [PDF]
, 2011 Aromatic amines during peroxidase metabolism produce N-centered cationic radicals and phenyl radicals as reactive intermediates. The latter also induce protein oxidation. These findings are associated with drug induced agranulocytosis.
NARWALEY, MALYAJ
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