Results 21 to 30 of about 13,471,027 (144)
THE USE OF EVOKED ENDOCARDIAL RESPONSE FOR ASSESSMENT OF ANTIARRHYTHMIC DRUG EFFECTS ON MYOCARDIUM [PDF]
The technique “asymmetric biphasic stimulation” which paces the heart and neutralizes the post-stimulus polarization at the electrode-tiessue interface allows for the recording of the entire evoked endocardial response via a single electrode for both ...
Tetsushi, FURUKAWA +2 more
core +1 more source
Effects of antiarrhythmic drugs on phospholipid metabolism in Jurkat T cells The potassium channel blocker, clofilium, specifically increases phosphatidylserine synthesis [PDF]
Five antiarrhythmic drugs (bretylium, clofilium, propranolol, N-acetylprocainamide and amiodarone) were tested for their ability to modify phospholipid metabolism in Jurkat T lymphocytes.
Pelassy, Claudette +3 more
core +1 more source
We describe a single-run method for quantitating quinidine, procainamide, and N-acetylprocainamide, involving gas-liquid chromatography with a nitrogen-phosphorus selective detector. Within-run precision (CV) was 3% (x = 2 mg/L, n = 20), 6.9% (x = 4 mg/L,
Kessler, K M +6 more
core +1 more source
Reduced acetylation of procainamide by para-aminobenzoic acid [PDF]
Acetylation is the major route of metabolism of many drugs including the antiarrhythmic agent procainamide. Coadministration of para-aminobenzoic acid was observed to decrease the biotransformation of procainamide to N-acetylprocainamide in a patient ...
Cohen, Andrew I. +4 more
core +1 more source
Simultaneous high performance liquid chromatographic determination of procainamide, N-acetylprocainamide, disopyramide, mono-N-dealkyldisopyramide, quinidine, and propranolol in serum [PDF]
We describe a method for the simultaneous high performance liquid chromatographic determination of several antiarrhythmic drugs and some of their metabolites after extraction from 2.5 ml of spiked pooled sera.
Wesley, James F.
core +1 more source
Micellar liquid chromatography was employed for the monitoring of procainamide and its metabolite N-acetylprocainamide using a C18 column. Sodium dodecyl sulphate (SDS) and modifier concentrations were optimised in order to obtain minimum analysis time ...
Rambla Alegre, María +4 more
core +1 more source
N\AThis paper explores the integration of Unmanned Aerial Systems (UAS) for 3D terrain mapping and autonomous navigation, emphasizing the fusion of advanced technologies such as multi-camera setups and reinforcement learning (RL).
Baston, George
core +3 more sources
The electrophysilogic effects of N-acetylprocainamide (NAPA), a metabolite of procainamide reported to exert significant Class III antiarrhythmic effects in the adult heart. were evaluated in 12 neonatal mongrel canines (ages 7-14 days).
Dise, Theresa +3 more
core +1 more source
Flow rate, protein level and pH of mandibular and parotid saliva samples in rats were almost stabilized 2h after induction of salivation with pilocarpine (9ṁ0 mg h−1 kg−1). Salivary excretion profiles of procainamide, 50 mg kg−1 i.v., and its
Jun Watanabe +3 more
core +1 more source

