Directed evolution of Vibrio fischeri LuxR for improved response to butanoyl-homoserine lactone [PDF]
LuxR is the 3-oxohexanoyl-homoserine lactone (3OC6HSL) dependent transcriptional activator of the prototypical acyl-homoserine lactone (AHL) quorum sensing system of Vibrio fischeri.
Arnold, Frances H. +4 more
core +3 more sources
Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa [PDF]
The pathogenesis of Pseudomonas aeruginosa is associated with expression of virulence factors, many of which are controlled by two N:-acylhomoserine lactone (AHL)-based quorum-sensing systems. Escherichia coli strains equipped with a luxR-based monitor system expressing green fluorescent protein (GFP) in the presence of exogenous AHL molecules were ...
Wu, H +10 more
openaire +3 more sources
Have You Heard of Bonnie Bassler? A Historical Perspective on a Remarkable Career
Abstract The area of chemical communication in bacteria has grown explosively since the end of the 20th century. Among a number of key individuals and seminal findings that broke open this area of microbiology, the contributions of Bonnie Bassler and her colleagues are immense and multi‐layered.
Clay Fuqua
wiley +1 more source
Quorum Quenching Bacillus sonorensis Isolated from Soya Sauce Fermentation Brine
An N-acylhomoserine lactone (AHL)-degrading bacterial strain, L62, was isolated from a sample of fermentation brine of Chinese soya sauce by using rich medium agar supplemented with soya sauce (10% v/v).
Kok-Gan Chan +4 more
doaj +1 more source
Implications of Rewiring Bacterial Quorum Sensing [PDF]
Bacteria employ quorum sensing, a form of cell-cell communication, to sense changes in population density and regulate gene expression accordingly.
Arnold, Frances H., Haseltine, Eric L.
core +4 more sources
The pathogen Pseudomonas aeruginosa uses quorum sensing (QS) to control virulence and biofilm formation. Enzymatic disruption of quorum sensing is a promising anti-infection therapeutic strategy that does not rely on antibiotics.
Xinjiong Fan +5 more
doaj +1 more source
Quorum Sensing: suatu Sistem Komunikasi Bakteri Fitopatogen, Peranannya pada Proses Infeksi, dan Peluangnya sebagai Basis Pengembangan Strategi Baru dalam Pengendalian Penyakit Tumbuhan [PDF]
Previously, it is thought that bacterium is an autonomous unicellular organism with no capacity for collective behavior. Now the paradigm has changed since there are communication between intercell bacteria.
Hadiwiyono, H. (Hadiwiyono)
core +2 more sources
Two microbial isolates from a Malaysian shoreline were found to be capable of degrading N-acylhomoserine lactones. Both Matrix Assisted Laser Desorption Ionization-Time of Flight-Mass Spectrometry and 18S rDNA phylogenetic analyses confirmed that these ...
Norshazliza Ab Ghani +5 more
doaj +1 more source
Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
A Bultreys +38 more
core +1 more source
N-Acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms [PDF]
Pseudomonas aeruginosa and Burkholderia cepacia are capable of forming mixed biofilms in the lungs of cystic fibrosis patients. Both bacteria employ quorum-sensing systems, which rely on N-acylhomoserine lactone (AHL) signal molecules, to co-ordinate expression of virulence factors with the formation of biofilms. As both bacteria utilize the same class
Riedel, K. +9 more
openaire +2 more sources

