Results 41 to 50 of about 783,982 (246)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Properties of galaxy clusters in N-body simulations: Intrinsic properties [PDF]

open access: yes, 1997
We study the influence of the various parameters of scenarios of large-scale structure formation on properties of galaxy clusters, and investigate which cluster properties are most sensitive to these parameters.
de Theije, Pascal   +2 more
core   +4 more sources

The BEHOMO project: $Λ$LTB $N$-body simulations

open access: yesarXiv.org, 2022
Our Universe may feature large-scale inhomogeneities and anisotropies which cannot be explained by the standard model of cosmology, that is, the homogeneous and isotropic FLRW metric, on which the $Λ$CDM model is built, may not describe accurately observations.
Marra, V.   +4 more
openaire   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

NBODY6++GPU: Ready for the gravitational million-body problem

open access: yes, 2015
Accurate direct $N$-body simulations help to obtain detailed information about the dynamical evolution of star clusters. They also enable comparisons with analytical models and Fokker-Planck or Monte-Carlo methods.
Aarseth, Sverre   +6 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

A Relativistic view on large scale N-body simulations

open access: yes, 2014
We discuss the relation between the output of Newtonian N-body simulations on scales that approach or exceed the particle horizon to the description of General Relativity.
Rampf, Cornelius   +2 more
core   +1 more source

Dark matter with n-body numerical simulations

open access: yesRevista Mexicana de Física E, 2020
The development of numerical N-body simulations have allowed studying the formation process and evolution of galaxies at different scales. This paper presents the fundamental concepts of N-body systems applied to the cosmological evolution of the ¤-Cold Dark Matter (¤CDM) model. To perform structure formation in the Universe, we provide an introduction
Chacon, Jazhiel   +2 more
openaire   +3 more sources

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi   +9 more
wiley   +1 more source

Comments on the size of the simulation box in cosmological N-body simulations [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2005
N-Body simulations are a very important tool in the study of formation of large scale structures. Much of the progress in understanding the physics of high redshift universe and comparison with observations would not have been possible without N-Body simulations.
Bagla, J. S., Ray, Suryadeep
openaire   +2 more sources

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