Results 31 to 40 of about 2,754 (217)
PLoS ONE, 2012 The cadherin switch from E-cadherin to N-cadherin is considered as a hallmark of the epithelial-mesenchymal transition and progression of carcinomas. Although it enhances aggressive behaviors of adenocarcinoma cells, the significance and role of cadherin
Takashi Hashimoto +7 more
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Soluble N-cadherin fragment promotes angiogenesis [PDF]
Clinical & Experimental Metastasis, 2006 Endothelial cells express two dependent intercellular adhesion molecules: vascular endothelial (VE)-cadherin, specific for endothelial cells, and N-cadherin, also present in neuronal, lens, skeletal and heart muscle cells, osteoblasts, pericytes and fibroblasts.
DERYCKE L +5 more
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Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowth
eLife, 2020 Dynamic mechanical interactions between adhesion complexes and the cytoskeleton are essential for axon outgrowth and guidance. Whether planar cell polarity (PCP) proteins, which regulate cytoskeleton dynamics and appear necessary for some axon guidance ...
Steve Dos-Santos Carvalho +9 more
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Cell death in therapy, 2015 AbstractN-cadherin is an adhesion protein, which is important for intercellular interaction. It is involved in cell migration and motility during embryonic development, neuronal synapsis and cancer metastasis. There are several signaling cascades affected by N-cadherin including TGF-β, Rho family. N-cadherin is associated at the cytoplasmic domain with
Garima Sinha, Pranela Rameshwar
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Biology Open, 2019 N-cadherin mediates cell–cell contacts in vascular smooth muscle cells (VSMCs), and regulates VSMC behaviours including migration and proliferation. Discoidin domain receptor 1 (DDR1) is a collagen binding receptor also implicated in these processes ...
Songyi Xu +2 more
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Soluble N‐cadherin in human biological fluids [PDF]
International Journal of Cancer, 2006 AbstractClassical cadherins such as E‐, P‐ and N‐cadherin are transmembrane proteins that mediate cell–cell adhesion, and are important in embryogenesis, maintenance of tissue integrity and cancer. Proteolytic shedding of the extracellular domain results in the generation of soluble E‐, P‐ or N‐cadherin ectodomains.
Lara, Derycke +6 more
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Regulation of AMPA receptor trafficking by N‐cadherin [PDF]
Journal of Neurochemistry, 2006 AbstractDendritic spines are dynamically regulated, both morphologically and functionally, by neuronal activity. Morphological changes are mediated by a variety of synaptic proteins, whereas functional changes can be dramatically modulated by the regulation of α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate (AMPA) receptor trafficking.
Mutsuo, Nuriya, Richard L, Huganir
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Prognostic significance of E-cadherin and N-cadherin expression in Gliomas
BMC Cancer, 2017 Background Epithelial-mesenchymal transition (EMT), principally involving an E-cadherin to N-cadherin shift, linked to tumor invasion or metastasis, and therapeutic resistance in various human cancer.
Myung-Giun Noh +9 more
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Loss of N-Cadherin Expression in Tumor Transplants Produced From As+3- and Cd+2-Transformed Human Urothelial (UROtsa) Cell Lines. [PDF]
PLoS ONE, 2016 BACKGROUND:Epithelial to mesenchymal transition is a process in which a cell experiences a loss of epithelial cell characteristics and acquires a more mesenchymal cell phenotype.
Elizabeth J Sandquist +6 more
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Expression of N-Cadherin in Salivary Gland Tumors [PDF]
Medical Principles and Practice, 2012 <b><i>Objective:</i></b> To detect immunohistochemically the N-cadherin expression in different types of benign and malignant salivary gland tumors in an attempt to note any possible correlation to their development, stage and invasive properties. <b><i>Materials and Methods:</i></b> N-cadherin expression
Kehagias, N. +5 more
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