Results 21 to 30 of about 156,179 (265)
Asymmetric N-cadherin expression results in synapse dysfunction, synapse elimination, and axon retraction in cultured mouse neurons. [PDF]
PLoS ONE, 2013 Synapse elimination and pruning of axon collaterals are crucial developmental events in the refinement of neuronal circuits. While a control of synapse formation by adhesion molecules is well established, the involvement of adhesion molecules in ...
Kim N Pielarski +6 more
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N‐cadherin promoter polymorphisms and risk of osteoarthritis [PDF]
The FASEB Journal, 2013 Osteoarthritis (OA) is the most common form of arthritis. It is characterized by cartilage destruction and bone remodeling, mediated in part by synovial fibroblasts (SFs). Given the functional significance of cadherins in these cells, we aimed at determining the role of genetic variants of N‐cadherin (CDH2)
Anke, Ruedel +8 more
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N-cadherin: A new player in neuronal polarity [PDF]
Cell Cycle, 2012 Comment on: Gärtner A, et al.
Gartner A, Fornasiero E, Dotti CG
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N-cadherin, spine dynamics, and synaptic function [PDF]
frontiers in Neuroscience, 2008 Dendritic spines are one-half (the postsynaptic half) of most excitatory synapses. Ever since the direct observation over a decade ago that spines can continually change size and shape, spine dynamics has been of great research interest, especially as a mechanism for structural synaptic plasticity.
Mysore, S., Tai, C., Schuman, E.
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N-cadherin: stabilizing synapses [PDF]
Journal of Cell Biology, 2010 Spines are sites of excitatory synapse formation in central neurons. Alterations in spine structure and function are widely believed to actively contribute to the cellular mechanisms of learning and memory. In this issue, Mendez et al. (2010. J. Cell Biol.
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Aberrant N-cadherin expression in cancer
Biomedicine & Pharmacotherapy, 2019 Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and ...
Zhan-Qi, Cao, Zhi, Wang, Ping, Leng
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Clinics, 2011 OBJECTIVE: To evaluate the expression of the cell adhesion molecules E-cadherin and N-cadherin and the transcription factor Snail in invasive ductal breast carcinomas and to determine their relationships with clinicopathological features.
Hanan Mohamed Abd ElMoneim +1 more
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Expression of N-Cadherin in Salivary Gland Tumors [PDF]
Medical Principles and Practice, 2012 <b><i>Objective:</i></b> To detect immunohistochemically the N-cadherin expression in different types of benign and malignant salivary gland tumors in an attempt to note any possible correlation to their development, stage and invasive properties. <b><i>Materials and Methods:</i></b> N-cadherin expression
Kehagias, N. +5 more
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N-Cadherin Prodomain Processing Regulates Synaptogenesis [PDF]
The Journal of Neuroscience, 2012 Classical cadherins, which are adhesion molecules functioning at the CNS synapse, are synthesized as adhesively inactive precursor proteins in the endoplasmic reticulum (ER). Signal sequence and prodomain cleavage in the ER and Golgi apparatus, respectively, activates their adhesive properties.
Reines, Analia Gabriela +8 more
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Mbt/PAK4 together with SRC modulates N-Cadherin adherens junctions in the developing Drosophila eye
Biology Open, 2019 Tissue morphogenesis is accompanied by changes of adherens junctions (AJ). During Drosophila eye development, AJ reorganization includes the formation of isolated N-Cadherin AJ between photoreceptors R3/R4.
Stephanie M. Pütz
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