Results 211 to 220 of about 13,066,219 (329)

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui, Elena N. Kitova, Ling Han, Lara K. Mahal, John S. Klassen   +4 more
wiley   +1 more source

Simple capillary electrophoresis-mass spectrometry method for complex glycan analysis using a flow-through microvial interface.

Analytical Chemistry, 2014
R. Jayo, M. Thaysen‐Andersen, P. Lindenburg, R. Haselberg, T. Hankemeier, R. Ramautar, D. Chen   +6 more
semanticscholar   +1 more source

Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science

Mass Spectrometry Reviews, EarlyView.
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song, HyunJi Lee, Youngshik Choe, Hyeyoung Lee   +3 more
wiley   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

Pediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie, Qian Zhou, Jianxiang Liao, Yuejie Zheng, Wenjian Wang, Kunling Shen   +5 more
wiley   +1 more source

Immune Evasion of Porcine Reproductive and Respiratory Syndrome Virus through Glycan Shielding Involves both Glycoprotein 5 as Well as Glycoprotein 3

Journal of Virology, 2011
H. Vu, B. Kwon, K. Yoon, W. Laegreid, A. K. Pattnaik, F. Osorio   +5 more
semanticscholar   +1 more source

CRPPA exon 6–9 deletion as a founder mutation in Chinese patients with dystroglycanopathy

Pediatric Investigation, EarlyView.
Analysis of sixteen Chinese dystroglycanopathy patients reveals a founder mutation (CRPPA exon 6–9 deletion) in 25% of cases and expands the phenotypic spectrum from severe muscle‐eye‐brain disease to limb‐girdle muscular dystrophy. ABSTRACT Importance Dystroglycanopathies (DGPs) are a group of muscular dystrophies with abnormal glycosylation of ...
Jihang Luo, Yidan Liu, Danyu Song, Shiqi Yang, Xiaona Fu, Lin Ge, Cuijie Wei, Liya Cui, Yanbin Fan, Huaxia Luo, Yanwei He, Jin Xu, Qiang Shen, Yuxuan Guo, Motoi Kanagawa, Tatsushi Toda, Jingmin Wang, Hong Zhang, Hui Xiong   +18 more
wiley   +1 more source

Mass spectrometry imaging reveals alterations in protein and N-glycan molecular signatures in endometriosis tissues. [PDF]

Anal Bioanal Chem
Lin M, Seeley EH, Ledet S, Salazar C, Breen MT, Eberlin LS.   +5 more
europepmc   +1 more source

Enzymatic Basis for N-Glycan Sialylation [PDF]

Journal of Biological Chemistry, 2013
Lu Meng, Farhad Forouhar, David Thieker, Zhongwei Gao, Annapoorani Ramiah, Heather Moniz, Yong Xiang, Jayaraman Seetharaman, Sahand Milaninia, Min Su, Robert Bridger, Lucas Veillon, Parastoo Azadi, Gregory Kornhaber, Lance Wells, Gaetano T. Montelione, Robert J. Woods, Liang Tong, Kelley W. Moremen   +18 more
openaire   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Crystal structure of the fungal mannosyltransferase Och1 reveals active site primed for N-glycan binding. [PDF]

PLoS One
Kelly ETR, Rodionov D, Sleno B, Romero PA, Berghuis AM.   +4 more
europepmc   +1 more source