Results 231 to 240 of about 13,066,219 (329)

Proteomic Profiling of Alveolar Macrophages Identifies Loss of Lysosomal Content as an Indicator of Nanofiber‐Induced Frustrated Phagocytosis

Small, EarlyView.
This proteomic study examines how nanofibers affect lung macrophages by analyzing protein changes following exposure to various fibrous materials. Nanofibers triggered the release of inflammatory enzymes, and importantly, lysosomal content release was identified as an early event associated with frustrated phagocytosis. Seventeen sensitive and relevant
Tobias Stobernack, Antje Vennemann, Carla Ribalta, Julia Schendel, Oliver Gräb, Rico Ledwith, Mario Pink, Andrea Haase, Martin Wiemann, Verónica I. Dumit   +9 more
wiley   +1 more source

CRISPR screens and lectin microarrays identify high mannose N-glycan regulators. [PDF]

Nat Commun
Tsui CK, Twells N, Durieux J, Doan E, Woo J, Khosrojerdi N, Brooks J, Kulepa A, Webster B, Mahal LK, Dillin A.   +10 more
europepmc   +1 more source

Rapid Structural Analysis of Natural Products Using MicroED

Small, EarlyView.
The cryoEM method, MicroED used for rapid analysis and structure determination of natural products that remained unattainable by other structural biology methods ABSTRACT Structural analysis of natural products remains challenging due to their inherent complexity and limited availability.
Jieye Lin, Orel Paz, Johan Unge, Tamir Gonen   +3 more
wiley   +1 more source

Streamlined gram-scale natural N-glycan production using reversible tagging after oxidative release of natural glycans. [PDF]

Commun Chem
Zhang Q, Lasanajak Y, Yan M, Chen G, Song X.   +4 more
europepmc   +1 more source

Analysis of the human cancer glycome identifies a novel group of tumor-associated N-acetylglucosamine glycan antigens.

Cancer Research, 2009
T. Satomaa, A. Heiskanen, I. Leonardsson, J. Ångström, Anne Olonen, M. Blomqvist, Noora Salovuori, C. Haglund, S. Teneberg, J. Natunen, O. Carpén, J. Saarinen   +11 more
semanticscholar   +1 more source

Mechanism elucidation of cell‐selective fluorescent probes

Smart Molecules, EarlyView.
This perspective outlines five mechanistic strategies—Protein‐oriented, carbohydrate‐oriented, lipid‐oriented, gating‐oriented, and metabolism‐oriented live‐cell distinctions—for achieving cell‐selective fluorescence in live‐cell imaging. By classifying probes based on their interactions with proteins, carbohydrates, lipids, transporters, or metabolic ...
Sourav Sarkar, Young‐Tae Chang
wiley   +1 more source

N-deglycosylation targeting chimera (DGlyTAC): a strategy for immune checkpoint proteins inactivation by specifically removing N-glycan. [PDF]

Signal Transduct Target Ther
Li L, Wu J, Cao W, Zhang W, Wu Q, Li Y, Yang Y, Shan Z, Zheng Z, Ge X, Lin L, Wang P.   +11 more
europepmc   +1 more source

Site-specific glycan analysis of human chorionic gonadotropin beta-subunit from malignancies and pregnancy by liquid chromatography--electrospray mass spectrometry.

Glycobiology, 2006
L. Valmu, H. Alfthan, K. Hotakainen, S. Birken, U. Stenman   +4 more
semanticscholar   +1 more source

Nanopore Trap for Label‐Free Fingerprinting of Surface‐modified Single Nanoparticles

Small Methods, EarlyView.
A solid‐state nanopore trapping‐based methodology combines “trap‐release” measurement protocol with multiple features extracted from ionic current of trapping events to generate unique electrical fingerprints of nanoparticles with distinct surface functional layers.
Nianduo Cai, Tzu‐Heng Chen, Yunfei Teng, Akhil Sai Naidu, Aleksandra Radenovic   +4 more
wiley   +1 more source

N-glycan shielded CUB domains of ADAMTS13 prevent binding of C-terminal antibodies in patients with immune-mediated TTP. [PDF]

Blood Adv
Postmus T, Schilder N, Ferreira de Santana J, Langerhorst P, Kaijen P, Coppo P, Joly BS, Veyradier A, Vanhoorelbeke K, Voorberg J.   +9 more
europepmc   +1 more source