Results 71 to 80 of about 13,352,036 (198)

Site-specific glycan analysis of human chorionic gonadotropin beta-subunit from malignancies and pregnancy by liquid chromatography--electrospray mass spectrometry.

Glycobiology, 2006
Glycosylation is an important posttranslational modification in proteins, and aberrant glycosylation occurs in malignancies. Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced in high concentrations during pregnancy.
L. Valmu, H. Alfthan, K. Hotakainen, S. Birken, U. Stenman   +4 more
semanticscholar   +1 more source

Extensive Determination of Glycan Heterogeneity Reveals an Unusual Abundance of High Mannose Glycans in Enriched Plasma Membranes of Human Embryonic Stem Cells*

Molecular & Cellular Proteomics, 2011
Most cell membrane proteins are known or predicted to be glycosylated in eukaryotic organisms, where surface glycans are essential in many biological processes including cell development and differentiation.
H. An, Phung Gip, Jaehan Kim, Shuai Wu, Kun-Wook Park, C. T. McVaugh, D. Schaffer, C. Bertozzi, C. Lebrilla   +8 more
semanticscholar   +1 more source

Identification and Characterization of the Unique N-Linked Glycan Common to the Flagellins and S-layer Glycoprotein of Methanococcus voltae*

Journal of Biological Chemistry, 2005
The flagellum of Methanococcus voltae is composed of four structural flagellin proteins FlaA, FlaB1, FlaB2, and FlaB3. These proteins possess a total of 15 potential N-linked sequons (NX(S/T)) and show a mass shift on an SDS-polyacrylamide gel indicating
S. Voisin, R. Houliston, J. Kelly, J. Brisson, D. Watson, S. Bardy, K. Jarrell, S. Logan   +7 more
semanticscholar   +1 more source

Identification and comparison of N-glycome profiles from common dietary protein sources

Food Chemistry: X
The N-glycomes of bovine whey, egg white, pea, and soy protein isolates are described here. N-glycans from four protein isolates were analyzed by HILIC high performance liquid chromatography and quadrupole time-of-flight tandem mass spectrometry (HILIC ...
Matthew Bolino, İzzet Avcı, Hacı Mehmet Kayili, Hatice Duman, Bekir Salih, Sercan Karav, Steven A. Frese   +6 more
doaj  

Semi-automated identification of N-Glycopeptides by hydrophilic interaction chromatography, nano-reverse-phase LC-MS/MS, and glycan database search.

Journal of Proteome Research, 2012
Glycoproteins fulfill many indispensable biological functions, and changes in protein glycosylation have been observed in various diseases. Improved analytical methods are needed to allow a complete characterization of this complex and common post ...
P. Pompach, K. Chandler, R. Lan, N. Edwards, R. Goldman   +4 more
semanticscholar   +1 more source

Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis

Journal of the American Chemical Society, 2012
Human IgG Fc glycosylation modulates immunological effector functions such as antibody-dependent cellular cytotoxicity and phagocytosis. Engineering of Fc glycans therefore enables fine-tuning of the therapeutic properties of monoclonal antibodies. The N-
Thomas A Bowden, Kavitha Baruah, Charlotte H. Coles, David J. Harvey, Xiaojie Yu, B. Song, David I. Stuart, A. Aricescu, Christopher N. Scanlan, E. Y. Jones, M. Crispin   +10 more
semanticscholar   +1 more source

N-Linked Glycan Chains on S-Allele-Associated Glycoproteins from Nicotiana alata. [PDF]

, 1989
James R. Woodward, Antony Bacic, Willi Jahnen‐Dechent, Adrienne E. Clarke   +3 more
openalex   +1 more source

The GM2 glycan serves as a functional coreceptor for serotype 1 reovirus.

PLoS Pathogens, 2012
Viral attachment to target cells is the first step in infection and also serves as a determinant of tropism. Like many viruses, mammalian reoviruses bind with low affinity to cell-surface carbohydrate receptors to initiate the infectious process ...
Kerstin Reiss, Jennifer E Stencel, Yan Liu, Bärbel S Blaum, Dirk M Reiter, Ten Feizi, Terence S Dermody, Thilo Stehle   +7 more
doaj   +1 more source

Primary structure of a new tetraantennary glycan of the N-acetyllactosaminic type isolated from human factor VIII/von Willebrand factor [PDF]

, 1986
Bruno Samor, Jean‐Claude Michalski, Henri Debray, Claudine Mazurier, M Goudemand, H. van Halbeek, Johannes F.G. Vliegenthart, Jean Montreuil   +7 more
openalex   +1 more source

Glycan Microarray Analysis of P-type Lectins Reveals Distinct Phosphomannose Glycan Recognition*

Journal of Biological Chemistry, 2009
The specificity of the cation-independent and -dependent mannose 6-phosphate receptors (CI-MPR and CD-MPR) for high mannose-type N-glycans of defined structure containing zero, one, or two Man-P-GlcNAc phosphodiester or Man-6-P phosphomonoester residues ...
Xuezheng Song, Yi Lasanajak, L. Olson, Marielle Boonen, N. Dahms, S. Kornfeld, R. Cummings, David F. Smith   +7 more
semanticscholar   +1 more source