Results 81 to 90 of about 13,352,036 (198)

Serum IgG Glycan Hallmarks of Systemic Lupus Erythematosus

Engineering, 2023
Systemic lupus erythematosus (SLE) is a debilitating autoimmune disorder characterized by unknown pathogenesis and heterogeneous clinical manifestations.
Hudan Pan, Jingrong Wang, Yong Liang, Canjian Wang, Ruimin Tian, Hua Ye, Xiao Zhang, Yuanhao Wu, Miao Shao, Ruijun Zhang, Yao Xiao, Zhi Li, Guangfeng Zhang, Hua Zhou, Yilin Wang, Xiaoshuang Wang, Zhanguo Li, Wei Liu, Liang Liu   +18 more
doaj  

Comprehensive native glycan profiling with isomer separation and quantitation for the discovery of cancer biomarkers.

In Analysis, 2011
Glycosylation is highly sensitive to the biochemical environment and has been implicated in many diseases including cancer. Glycan compositional profiling of human serum with mass spectrometry has already identified potential biomarkers for several types
Serenus Hua, H. An, S. Ozcan, Grace S Ro, S. Soares, R. deVere-White, C. Lebrilla   +6 more
semanticscholar   +1 more source

The chemoenzymatic synthesis of glycan-terminated oligo(Leu)x

Frontiers in Catalysis
Introduction: Glycopeptides contain carbohydrate moieties (glycans) covalently attached to the side chain and/or terminal peptide units. Since glycans are present on cell surfaces, these constructs can potentially address a wide array of therapeutic ...
Sarah P. Black, Melinda Liu, Cesar Castillo, Wynne Coradeli, Filbert Totsingan, Cody B. Edson, Sagar D. Khare, Richard A. Gross   +7 more
doaj   +1 more source

Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells

Scientific Reports, 2018
Sialylation of recombinant therapeutic glycoproteins modulates their pharmacokinetic properties by affecting their in vivo half-life. N-glycan branching on glycoproteins increases the number of potential attachment sites for sialic acid.
Chung-Geun Lee, Myung Jin Oh, Seung-Yeol Park, Hyun Joo An, Jung Hoe Kim   +4 more
doaj   +1 more source

In the Biosynthesis of N‐Glycans in Connective Tissue of the Snail Lymnaea Stagnalis of Incorporation GlcNAc by β2GlcNAc‐transferase I is an essential prerequisite for the action of β2GlcNAc‐transferase II and β2Xyl‐transferase [PDF]

, 1995
Hans Mulder, Fabienne Dideberg, Harry Schachter, Bertina A. Spronk, Marijke de Jong‐Brink, Johannis P. Kamerling, Johannes F.G. Vliegenthart   +6 more
openalex   +1 more source

Complex N-glycans in Mgat1 null preimplantation embryos arise from maternal Mgat1 RNA [PDF]

, 1997
Ella Ioffe, Yun Liu, Pamela Stanley
openalex   +1 more source

Distinct CD16a features on human NK cells observed by flow cytometry correlate with increased ADCC

Scientific Reports
Natural killer (NK) cells destroy tissue that have been opsonized with antibodies. Strategies to generate or identify cells with increased potency are expected to enhance NK cell-based immunotherapies.
Maria C. Rodriguez Benavente, Zainab A. Hakeem, Alexander R. Davis, Nathan B. Murray, Parastoo Azadi, Emily M. Mace, Adam W. Barb   +6 more
doaj   +1 more source

Comparison of Four Rapid N-Glycan Analytical Methods and Great Application Potential in Cell Line Development

Applied Sciences
N-glycan, a critical quality attribute (CQA) of monoclonal antibodies, profoundly impacts potency, immunogenicity, safety, and clinical efficiency. Therefore, N-glycan should be monitored and controlled during development. The conventional 2-AB method is
Xiaoqing Jin, Jianlin Chu, Bingfang He
doaj   +1 more source

N-linked glycans containing linear poly-N-acetyllactosamine as sorting signals in endocytosis in Trypanosoma brucei [PDF]

, 1999
Derek P. Nolan, Maurice Geuskens, Etienne Pays   +2 more
openalex   +1 more source

Sulfated di‐, tri‐ and tetraantennary N‐glycans in human Tamm‐Horsfall glycoprotein [PDF]

, 1998
Johannes J.M. van Rooijen, Johannis P. Kamerling, Johannes F.G. Vliegenthart   +2 more
openalex   +1 more source