Interlinked GTPase cascades provide a motif for both robust switches and oscillators [PDF]
J. R. Soc. Interface 16, 20190198 (2019), 2019 GTPases regulate a wide range of cellular processes, such as intracellular vesicular transport, signal transduction, and protein translation. These hydrolase enzymes operate as biochemical switches by toggling between an active guanosine triphosphate (GTP)-bound state and an inactive guanosine diphosphate (GDP)-bound state.
arxiv +1 more source
Identification and analysis of seven effector protein families with different adaptive and evolutionary histories in plant-associated members of the Xanthomonadaceae. [PDF]
, 2017 The Xanthomonadaceae family consists of species of non-pathogenic and pathogenic γ-proteobacteria that infect different hosts, including humans and plants.
Almeida, Nalvo F +14 more
core +2 more sources
Molecular Plant-Microbe Interactions, 2000 Nod factors excreted by rhizobia are signal molecules that consist of a chitin oligomer backbone linked with a fatty acid at the nonreducing end. Modifications of the Nod factor structures influence their stability in the rhizosphere and their biological
Christian Staehelin +6 more
doaj +1 more source
Molecules, 2019 Salinity stress limited the production in over 30% of irrigated crops and 7% of dryland agriculture worldwide. The objective was to evaluate the effects of NaCl-stress on the enzymatic activity in tomato.
J. Reyes-Pérez +5 more
semanticscholar +1 more source
Family-specific scaling laws in bacterial genomes [PDF]
, 2017 Among several quantitative invariants found in evolutionary genomics, one of the most striking is the scaling of the overall abundance of proteins, or protein domains, sharing a specific functional annotation across genomes of given size.
de Lazzari, Eleonora +3 more
core +2 more sources
Frontiers in Plant Science, 2014 Colonization of the land by plants required major modifications in cellular structural composition and metabolism. Intercellular communication through plasmodesmata (PD) plays a critical role in the coordination of growth and cell activities.
Rocio Gaudioso-Pedraza +1 more
semanticscholar +1 more source
Machine learning on DNA-encoded libraries: A new paradigm for hit-finding [PDF]
, 2020 DNA-encoded small molecule libraries (DELs) have enabled discovery of novel inhibitors for many distinct protein targets of therapeutic value through screening of libraries with up to billions of unique small molecules. We demonstrate a new approach applying machine learning to DEL selection data by identifying active molecules from a large commercial ...
arxiv +1 more source
Comparative transcriptomics reveals key differences in the response to milk oligosaccharides of infant gut-associated bifidobacteria. [PDF]
, 2015 Breast milk enhances the predominance of Bifidobacterium species in the infant gut, probably due to its large concentration of human milk oligosaccharides (HMO). Here we screened infant-gut isolates of Bifidobacterium longum subsp.
Garrido, Daniel +5 more
core +2 more sources
Catalysis by hen egg-white lysozyme proceeds via a covalent intermediate [PDF]
, 2001 Hen egg-white lysozyme (HEWL) was the first enzyme to have its three-dimensional structure determined by X-ray diffraction techniques(1). A catalytic mechanism, featuring a long-lived oxo-carbenium-ion intermediate, was proposed on the basis of model ...
A Federov +28 more
core +1 more source
Identification and Expression of Some Plant Cell Wall-Degrading Enzymes Present in Three Ontogenetics Stages of Thecaphora frezii, a Peanut (Arachis hypogaea L.) Pathogenic Fungus [PDF]
, 2022 Peanuts can be affected by the presence of pathogenic microorganisms. The fungus Thecaphora frezii (T. frezii), which belongs to the taxonomic class Ustilaginomycetes, is the causal agent of the disease known as “peanut smut”.
Alasino, Roxana Valeria +5 more
core +1 more source