Results 1 to 10 of about 183,842 (201)

Metabolic versatility of Acinetobacter baumannii: distinct pathways for the utilization of short-, medium- and long-chain acyl-L-carnitines [PDF]

open access: yesFrontiers in Microbiology
Acinetobacter baumannii is a multidrug-resistant pathogen capable of metabolizing host-derived acyl-L-carnitines, which contributes to its virulence. During A.
Paula Schwerdhelm   +9 more
doaj   +2 more sources

A Universal Structural Grammar in Enzyme Fold for Predicting Drug Target Stability: Deciphering Directional Scaffolding via Multi-Stage Pearson Correlation of Asymmetric Contact Matrices [PDF]

open access: yesPharmaceutics
Background/Objectives: Traditional protein contact analysis often fails to distinguish between local, sequence-driven motifs and global, tertiary scaffolding, which ensures structural determinism.
Fatin Jannus, Hilario Ramírez-Rodrigo
doaj   +2 more sources

Catalysis by Nucleoside Hydrolases [PDF]

open access: yesCurrent Opinion in Structural Biology, 2003
Nucleoside hydrolases cleave the N-glycosidic bond of ribonucleosides. Because of their vital role in the protozoan purine salvage pathway, nucleoside hydrolases from parasitic protozoa in particular have been studied extensively by X-ray crystallography, kinetic methods and site-directed mutagenesis.
Jan Steyaert, Wim Versées
exaly   +4 more sources

Role of Seasonality and Fire in Regulating the Enzymatic Activities in Soils Covered by Different Vegetation in a Mediterranean Area

open access: yesApplied Sciences, 2021
As they quickly respond to environmental conditions, soil enzymes, involved in nutrient cycles, are considered good indicators of soil quality. The Mediterranean area is a peculiar environment for climatic conditions and for fire frequency.
Valeria Memoli   +8 more
doaj   +1 more source

Biochemical and Multi-Omics Approaches To Obtain Molecular Insights into the Catabolism of the Plasticizer Benzyl Butyl Phthalate in Rhodococcus sp. Strain PAE-6

open access: yesMicrobiology Spectrum, 2023
Phthalate diesters are extensively used as plasticizers in manufacturing plastic materials; however, because of their estrogenic properties, these chemicals have emerged as a global threat to human health.
Suman Basu   +3 more
doaj   +1 more source

Screening of halotolerant microfungi isolated from hypersaline soils of Algerian Sahara for production of hydrolytic enzymes

open access: yesJournal of Biological Research, 2021
The Algerian Sahara contains numerous hypersaline ecosystems including salt lakes in which the fungal diversity has not been characterized. The abundance and diversity of soil microofungi in three salt lakes in southeastern Algeria was investigated ...
Wassila Dendouga, Mohamed Belhamra
doaj   +1 more source

Induction and Repression of Hydrolase Genes in Aspergillus oryzae

open access: yesFrontiers in Microbiology, 2021
The filamentous fungus Aspergillus oryzae, also known as yellow koji mold, produces high levels of hydrolases such as amylolytic and proteolytic enzymes. This property of producing large amounts of hydrolases is one of the reasons why A.
Mizuki Tanaka, Katsuya Gomi
doaj   +1 more source

Predicting Bacteriophage Enzymes and Hydrolases by Using Combined Features

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Bacteriophage is a type of virus that could infect the host bacteria. They have been applied in the treatment of pathogenic bacterial infection. Phage enzymes and hydrolases play the most important role in the destruction of bacterial cells.
Hong-Fei Li   +3 more
doaj   +1 more source

A Hydrolase Produced by Rhodococcus erythropolis HQ Is Responsible for the Detoxification of Zearalenone

open access: yesToxins, 2023
Zearalenone (ZEN), an estrogenic mycotoxin, is one of the prevalent contaminants found in food and feed, posing risks to human and animal health. In this study, we isolated a ZEN-degrading strain from soil and identified it as Rhodococcus erythropolis HQ.
Junqiang Hu   +8 more
doaj   +1 more source

Characterization of Some Salt-Tolerant Bacterial Hydrolases with Potential Utility in Cultural Heritage Bio-Cleaning

open access: yesMicroorganisms, 2022
Salt-tolerant enzymes produced by halophilic and halotolerant microorganisms have been proposed to be used in various applications that involve high saline conditions.
Robert Ruginescu   +8 more
doaj   +1 more source

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