Results 11 to 20 of about 180,264 (297)

A Universal Structural Grammar in Enzyme Fold for Predicting Drug Target Stability: Deciphering Directional Scaffolding via Multi-Stage Pearson Correlation of Asymmetric Contact Matrices [PDF]

Pharmaceutics
Background/Objectives: Traditional protein contact analysis often fails to distinguish between local, sequence-driven motifs and global, tertiary scaffolding, which ensures structural determinism.
Fatin Jannus, Hilario Ramírez-Rodrigo
doaj   +2 more sources

Isolation and Determination of Bile Salt Hydrolase-Producing Lactic Acid Bacteria from Fermented Spider Plant

Journal of Pure and Applied Microbiology, 2018
Bile salt hydrolase is an enzyme from bacteria that can hydrolyze bile acid to be insoluble form and this event lead to reducing of cholesterol level in serum.
Atipat Yasiri, Emilie Vannaxay, Jinatta Kiatmontri, Supawadee Seubsasana   +3 more
doaj   +2 more sources

GGH (gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on GGH (gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase), with data on DNA, on the protein encoded, and where the gene is implicated.
Cheng, Q, Evans, WE
openaire   +4 more sources

Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase [PDF]

Journal of Lipid Research, 2011
Hepoxilins are lipid signaling molecules derived from arachidonic acid through the 12-lipoxygenase pathway. These trans-epoxy hydroxy eicosanoids play a role in a variety of physiological processes, including inflammation, neurotransmission, and formation of skin barrier function.
Cronin, A, Decker, M, Arand, Michael
openaire   +7 more sources

Microsomal epoxide hydrolase is not a 2-arachidonyl glycerol hydrolase [PDF]

Matters, 2016
The endocannabinoid 2-arachidonyl glycerol (2-AG) is substantially hydrolysed by at least two enzymes, fatty acid amide hydrolase (FAAH) and monoarachidonyl glycerol lipase (MAGL), which thereby terminate its biological activity. In a recent report it has been claimed that microsomal epoxide hydrolase (mEH), hitherto known as a xenobiotic detoxifying ...
Arand, Michael, Marowsky, Anne
openaire   +4 more sources

A minimal cellulosome-like system in Cellulosilyticum lentocellum. [PDF]

FEBS Open Bio
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
Allan J, Alstrom-Moore A, Black GW.
europepmc   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum. [PDF]

FEBS Open Bio
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Delgado-Rey A, Llamas-García ML, Montero-Morán GM, Santos L, Lara-González S.   +4 more
europepmc   +2 more sources

Role of Seasonality and Fire in Regulating the Enzymatic Activities in Soils Covered by Different Vegetation in a Mediterranean Area

Applied Sciences, 2021
As they quickly respond to environmental conditions, soil enzymes, involved in nutrient cycles, are considered good indicators of soil quality. The Mediterranean area is a peculiar environment for climatic conditions and for fire frequency.
Valeria Memoli, Lucia Santorufo, Giorgia Santini, Paola Musella, Rossella Barile, Anna De Marco, Gabriella Di Natale, Marco Trifuoggi, Giulia Maisto   +8 more
doaj   +1 more source

Biochemical and Multi-Omics Approaches To Obtain Molecular Insights into the Catabolism of the Plasticizer Benzyl Butyl Phthalate in Rhodococcus sp. Strain PAE-6

Microbiology Spectrum, 2023
Phthalate diesters are extensively used as plasticizers in manufacturing plastic materials; however, because of their estrogenic properties, these chemicals have emerged as a global threat to human health.
Suman Basu, Rinita Dhar, Mousumi Bhattacharyya, Tapan K. Dutta   +3 more
doaj   +1 more source

Screening of halotolerant microfungi isolated from hypersaline soils of Algerian Sahara for production of hydrolytic enzymes

Journal of Biological Research, 2021
The Algerian Sahara contains numerous hypersaline ecosystems including salt lakes in which the fungal diversity has not been characterized. The abundance and diversity of soil microofungi in three salt lakes in southeastern Algeria was investigated ...
Wassila Dendouga, Mohamed Belhamra
doaj   +1 more source