Results 41 to 50 of about 183,842 (201)

IFN-Induced PARPs—Sensors of Foreign Nucleic Acids?

Pathogens, 2023
Cells have developed different strategies to cope with viral infections. Key to initiating a defense response against viruses is the ability to distinguish foreign molecules from their own. One central mechanism is the perception of foreign nucleic acids
Katharina Biaesch, Sarah Knapp, Patricia Korn   +2 more
doaj   +1 more source

Production of tartaric acid using immobilized recominant cis-epoxysuccinate hydrolase

, 2017
To investigate the expression and immobilization of recombinant cis-epoxysuccinate hydrolase (ESH), and its application in the biological production of l-(+)-tartaric acid.
Wang, Ziqiang, Su, Munan, Wang, Yunshan, Li, Yanliang, Su, Zhiguo   +4 more
core   +1 more source

Construction of an engineered Bacillus subtilis for production of poly-γ-glutamic acids with specific molecular weights

Frontiers in Microbiology
IntroductionPoly-γ-glutamic acid (γ-PGA) with different molecular weight (Mw) exhibits different properties and therefore has a variety of applications. At present, the γ-PGA is mainly produced by Bacillus species.
Yu Lin, Yiwei Ding, Lin Shu, Lin Shu, Huizhen Chen, Nan Li, Xiaoqun Duan, Wei Zeng, Wei Zeng, Wei Zeng   +9 more
doaj   +1 more source

Metabolism of Zearalenone in the Rumen of Dairy Cows with and without Application of a Zearalenone-Degrading Enzyme

Toxins, 2021
The mycotoxin zearalenone (ZEN) is a frequent contaminant of animal feed and is well known for its estrogenic effects in animals. Cattle are considered less sensitive to ZEN than pigs.
Christiane Gruber-Dorninger, Johannes Faas, Barbara Doupovec, Markus Aleschko, Christian Stoiber, Andreas Höbartner-Gußl, Karin Schöndorfer, Manuela Killinger, Qendrim Zebeli, Dian Schatzmayr   +9 more
doaj   +1 more source

Kinetics, Thermodynamics and Mechanism of Enzymatic Degradation of Zearalenone in Degummed Corn Oil

Toxins, 2022
The kinetics and thermodynamics of the enzymatic degradation of zearalenone (ZEN) in degummed corn oil were investigated by analyzing the impacts of temperature, pH, ZEN hydrolase dosage and ZEN concentration on the initial reaction rate.
Chenwei Zhao, Pengkai Xie, Jun Jin, Qingzhe Jin, Xingguo Wang   +4 more
doaj   +1 more source

Enzymatic Degradation of Zearalenone in the Gastrointestinal Tract of Pigs, Chickens, and Rainbow Trout

Toxins, 2023
The estrogenic mycotoxin zearalenone (ZEN) is a common contaminant of animal feed. Effective strategies for the inactivation of ZEN in feed are required.
Christiane Gruber-Dorninger, Manuela Killinger, Andreas Höbartner-Gußl, Roy Rosen, Barbara Doupovec, Markus Aleschko, Heidi Schwartz-Zimmermann, Oliver Greitbauer, Zoran Marković, Marko Stanković, Karin Schöndorfer, Djuro Vukmirovic, Silvia Wein, Dian Schatzmayr   +13 more
doaj   +1 more source

Enhanced Response of a Proteinase K-Based Conductometric Biosensor Using Nanoparticles

Sensors, 2014
Proteinases are involved in a multitude of important physiological processes, such as protein metabolism. For this reason, a conductometric enzyme biosensor based on proteinase K was developed using two types of nanoparticles (gold and magnetic).
Wided Nouira, Abderrazak Maaref, Hamid Elaissari, Francis Vocanson, Maryam Siadat, Nicole Jaffrezic-Renault   +5 more
doaj   +1 more source

New Insights Into Human Hyaluronidase 4/Chondroitin Sulphate Hydrolase

Frontiers in Cell and Developmental Biology, 2021
In this review, the current experimental evidence, literature and hypotheses surrounding hyaluronidase 4 [HYAL4, also known as chondroitin sulphate hydrolase (CHSE)] and chondroitin sulphate (CS) are explored. Originally named for its sequence similarity
Marissa L. Maciej-Hulme
doaj   +1 more source

Cloning and characterization of the first member of the Nudix family from Arabidopsis thaliana. [PDF]

, 2002
The sequence motif commonly called a Nudix box, represented by (GX(5)EX(7)REVXEEXGU) is the marker of a widely distributed family of enzymes that catalyze the hydrolysis of a variety of nucleoside diphosphate derivatives. Here we describe the cloning and
Dobrzanska, Marta, Kraszewska, Elzbieta, Szurmak, Blanka, Wysłouch-Cieszyńska, Aleksandra   +3 more
core   +1 more source

MacroD1 Is a Promiscuous ADP-Ribosyl Hydrolase Localized to Mitochondria

Frontiers in Microbiology, 2018
MacroD1 is a macrodomain containing protein that has mono-ADP-ribose hydrolase enzymatic activity toward several ADP-ribose adducts. Dysregulation of MacroD1 expression has been shown to be associated with the pathogenesis of several forms of cancer.
Thomas Agnew, Deeksha Munnur, Kerryanne Crawford, Luca Palazzo, Andreja Mikoč, Ivan Ahel   +5 more
doaj   +1 more source