Results 71 to 80 of about 31,604 (216)
Integrative Zoology, EarlyView.This research reveals the gut microbiota‐mediated severe foraging environment adaptation of wild small ruminants in the Three‐River‐Source National Park. Unlike Tibetan sheep (TS), blue sheep (PN and Tibetan antelope (TA) often grazed low‐quality herbage in a wildness environment, and the higher microbial diversity and resilient network characteristics
Hongjin LIU +11 more
wiley +1 more source
Bioprospecting metagenomics of decaying wood: mining for new glycoside hydrolases [PDF]
, 2011 Background To efficiently deconstruct recalcitrant plant biomass to fermentable sugars in industrial processes, biocatalysts of higher performance and lower cost are required.
Adney, William S +12 more
core +3 more sources
The FEBS Journal, EarlyView.The multidomain glycosidase MDG from the hyperthermophilic euryarchaeon Thermococcus sp. contains five protein domains: three catalytic domains (GH5, GH12‐1, and GH12‐2) and two cellulose‐binding modules (CBM2). In this study, the GH12‐1 and GH12‐2 domains were individually purified and biochemically characterized.
Kseniya S. Zayulina +11 more
wiley +1 more source
In silico modeling of the molecular structure and binding of leukotriene A4 into leukotriene A4 hydrolase [PDF]
arXiv, 2012 A combined molecular docking and molecular structure in silico analysis on the substrate and product of leukotriene A4 hydrolase (LTA4H) was performed. The molecular structures of the substrate leukotriene A4 (LTA4) and product leukotirene B4 (LTB4) were studied through Density Functional Theory (DFT) calculations at the B3LYP/6-31+G(d) level of theory
arxiv
Families, superfamilies and subfamilies of glycosyl hydrolases.
Biochemical Journal, 1995 NAG Gga NAG Hsa GAL Hsa GAL Cte GAL Sce GAL Ani GAL Eco GAL Ppel GAL Ppe2 GAL Smu IMD Agi (53) LGYKYINIDDCWAAKQRDAE.. .GRLVPDPERFPRG (70) MOYTYLNIDDCWIG.GRDAS...GRLMPDPKRFPHG (84) AGYEYLCIDDCWMAPQRDSE...GRLQADPQRFPHG (90) LGYQYINLDDCWAELNRDSE ...
B. Henrissat, A. Romeu
semanticscholar +1 more source
Electrostatic potential as a reactivity scoring function in computer‐assisted enzyme engineering
The FEBS Journal, EarlyView.We present a computational metric that quantifies the electrostatic complementarity of enzymes to the charge distribution of substrates at the transition state. Implemented in BindScan, this metric accurately predicts functionally relevant mutations in glycoside hydrolases.
Aitor Vega, Antoni Planas, Xevi Biarnés
wiley +1 more source
Enzymatic conversion of β-mannans: Analysing, evaluating and modifying transglycosylation properties of glycoside hydrolases [PDF]
, 2022 Retaining glycoside hydrolases are enzymes that catalyse the breakdown down of glycans through hydrolysis. Due to the double-replacement mechanism of the retaining glycoside hydrolases (GHs), which form an intermediate with part of the glycan covalently ...
Wiemann, Mathias
core
Cellular and Molecular Life Sciences, 2020 The human body is able to process and transport a complex variety of carbohydrates, unlocking their nutritional value as energy source or as important building block.
H. Elferink +3 more
semanticscholar +1 more source
Journal of Integrative Plant Biology, EarlyView.The rice pollen‐specific receptor‐like kinases OsPRK1, OsPRK2, and OsPRK3 play a crucial role in reactive oxygen species (ROS)‐mediated pollen hydration and germination. Triple mutants display male sterility due to decreased ROS levels and impaired pollen hydration, and their germination phenotype can be partially restored by exogenous application of ...
Eui‐Jung Kim +9 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1995 The regions surrounding the catalytic amino acids previously identified in a few "retaining" O-glycosyl hydrolases (EC 3.2.1) have been analyzed by hydrophobic cluster analysis and have been used to define sequence motifs. These motifs have been found in
B. Henrissat +5 more
semanticscholar +1 more source