Results 171 to 180 of about 239,540 (278)

[Retracted] N‑Myc downstream‑regulated gene 2 suppresses the proliferation of T24 human bladder cancer cells via induction of oncosis. [PDF]

Mol Med Rep
Huang J, Wu Z, Wang G, Cai Y, Cai M, Li Y.   +5 more
europepmc   +1 more source

N-myc downstream regulated gene 1 inhibition of tumor progression in Caco2 cells. [PDF]

World J Gastrointest Oncol, 2022
He YX, Shen H, Ji YZ, Hua HR, Zhu Y, Zeng XF, Wang F, Wang KX.   +7 more
europepmc   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

A Small Molecule Selectively Targets N-Myc to Suppress Neuroblastoma Cancer Progression. [PDF]

Int J Biol Sci
Miao Y, Chen H, Li Y, Li L, Ye J, Zhang J, Wang J, Wu H, Li G, Chen Y, Yi Z, Liu M.   +11 more
europepmc   +1 more source

An immature, dedifferentiated, and lineage-deconstrained cone precursor origin of N-Myc-initiated retinoblastoma. [PDF]

Proc Natl Acad Sci U S A, 2022
Singh HP, Shayler DWH, Fernandez GE, Thornton ME, Craft CM, Grubbs BH, Cobrinik D.   +6 more
europepmc   +1 more source

N-Myc Proto-Oncogene Protein [PDF]

, 2020
openaire   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

Insights into retinoblastoma pathogenesis: unraveling RB1, N-MYC and miRNA profiles. [PDF]

BMJ Open Ophthalmol
Faranoush M, Khesali F, Faranoush P, Foroughi-Gilvaee MR, Shams P, Sadighnia N, Ahmadi SAY, Fallah Azad D, Nekouian R.   +8 more
europepmc   +1 more source

Retracted: N-myc Downstream-Regulated Gene 1 (NDRG1) Regulates Vascular Endothelial Growth Factor A (VEGFA) and Malignancies in Glioblastoma Multiforme (GBM). [PDF]

Biomed Res Int, 2023
International BR.
europepmc   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source