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Cancer Letters, 2003
Neuroblastomas are characterized by defects in tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induced apoptosis, especially down-regulation and methylation of Caspase-8 (CASP8). This defect is associated with amplification of N-myc.
van Noesel, Max M. +3 more
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Neuroblastomas are characterized by defects in tumor necrosis factor-related apoptosis inducing ligand (TRAIL) induced apoptosis, especially down-regulation and methylation of Caspase-8 (CASP8). This defect is associated with amplification of N-myc.
van Noesel, Max M. +3 more
openaire +4 more sources
Prolonged N-myc protein half-life in a neuroblastoma cell line lacking N-myc amplification.
Oncogene, 1991Genomic amplification of the oncogene N-myc is associated with rapid tumor progression and poor prognosis in patients with neuroblastoma (NB). However, 40% of NBs which lack N-myc amplification are also clinically aggressive. Factors other than N-myc copy number must therefore play a role in determining tumor progression in these NBs.
S L, Cohn +9 more
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N-myc Gene Amplification in Teratoma
JNCI Journal of the National Cancer Institute, 1990I, Ishiwata +8 more
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N-myc regulation in neuroblastoma
Cancer Genetics and Cytogenetics, 1994Cheng Ngan Ching +7 more
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SIRT1 promotes N-Myc oncogenesis stabilizing N-Myc protein
2011Marshall GM +12 more
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N-myc amplification in Wilms' tumor
Cancer Genetics and Cytogenetics, 1988Murray D. Norris +3 more
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