<b>ARNTL2 regulated the oncogene c-myc and promoted the progression of esophageal cancer through activating</b> <i><b>ANXA2</b></i> <b>transcription</b>. [PDF]
Qin Y +5 more
europepmc +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Activation of Kv11.1 potassium channel suppresses non-small cell lung cancer growth by promoting c-Myc degradation. [PDF]
Eskandari N +4 more
europepmc +1 more source
Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu +4 more
wiley +1 more source
Transcriptomics Analysis of the Adipogenic Differentiation Mechanism of Bovine Adipose-Derived Neural Crest Stem Cells. [PDF]
Zhang K, Tang X, Zhao R, Yan Y, Song X.
europepmc +1 more source
State‐of‐the‐Art Strategies for Circular RNA in Cancers: Opportunity and Challenge
Overview of circular RNA in tumors. ABSTRACT Circular RNAs (circRNAs) are characterized by their covalently closed structure, remarkable stability, and precise spatiotemporal regulation, evolving from once‐overlooked transcriptional byproducts to pivotal molecular regulators.
Zehao Ding +6 more
wiley +1 more source
The E3 ubiquitin ligase TRIM56 promotes aggregation and activation of Src protein through Lys63-linked polyubiquitination in hepatocellular carcinoma. [PDF]
Zhu L, Cui X, Xu H, Yang M, Han L.
europepmc +1 more source
Abstract Cervical cancer remains the fourth most common cancer affecting women worldwide, and incidences of other HPV‐related cancers continue to rise. For the development of effective prevention strategies in high‐risk patients, we aimed to better understand the roles of inflammatory pathways and the tumour microenvironment as the main driver of ...
Gianna Pavilion +9 more
wiley +1 more source
Editorial: Molecular mechanisms and treatment of MYCN-driven tumors, volume II. [PDF]
Zhu Y, Suenaga Y.
europepmc +1 more source
Molecular alterations in high‐grade neuroendocrine tumors of the small intestine
Abstract High‐grade neuroendocrine tumors of the small intestine are separated into two groups: well‐differentiated neuroendocrine tumors (NETs, high‐grade) and poorly differentiated neuroendocrine carcinomas (NECs). They represent very rare entities, with few molecular data available, and are very challenging to treat.
Agathe Hercent +9 more
wiley +1 more source

