Results 1 to 10 of about 13,188 (213)

Risk assessment of N‐nitrosamines in food [PDF]

open access: yesEFSA Journal, 2023
EFSA was asked for a scientific opinion on the risks to public health related to the presence of N‐nitrosamines (N‐NAs) in food. The risk assessment was confined to those 10 carcinogenic N‐NAs occurring in food (TCNAs), i.e. NDMA, NMEA, NDEA, NDPA, NDBA,
EFSA Panel on Contaminants in the Food Chain (EFSA CONTAM Panel)   +24 more
doaj   +5 more sources

Salmonella typhimurium TA100 and TA1535 and E. coli WP2 uvrA are highly sensitive to detect the mutagenicity of short Alkyl-N-Nitrosamines in the Bacterial Reverse Mutation Test [PDF]

open access: yesToxicology Reports, 2022
Humans are exposed to low levels of N-nitrosamines via different sources. N-Nitrosamines have recently been detected as impurities in various marketed drugs and they are known mutagenic carcinogens belonging to the cohort of concern as referred to in the
Frank Bringezu, Stephanie Simon
doaj   +2 more sources

Residual Nitrite, Nitrate, and Volatile N-Nitrosamines in Organic and Conventional Ham and Salami Products [PDF]

open access: yesFoods
Nitrite and nitrate in meat products may be perceived negatively by consumers. These compounds can react to form carcinogenic volatile N-nitrosamines.
Kathrine H. Bak   +3 more
doaj   +2 more sources

The Effect of Tobacco Smoke N-Nitrosamines, NNK and NDEA, and Nicotine, on DNA Mismatch Repair Mechanism and miRNA Markers, in Hypopharyngeal Squamous Cell Carcinoma: An In Vivo Model and Clinical Evidence [PDF]

open access: yesCurrent Oncology, 2022
Deregulation of the DNA mismatch repair (MMR) mechanism has been linked to poor prognosis of upper aerodigestive tract cancers. Our recent in vitro data have provided evidence of crosstalk between deregulated miRNAs and MMR genes, caused by tobacco smoke
Sotirios G. Doukas   +5 more
doaj   +2 more sources

Dietary exposure to N-nitrosamines and their precursors: an age-stratified assessment [PDF]

open access: yesScientific Reports
Dietary exposure to N-nitrosamines (N-NAs) may pose health concerns across all age groups, particularly in children and the elderly, due to their association with increased cancer risk.
Aida Zapico   +5 more
doaj   +2 more sources

Inhibition effect of non-contact biocontrol bacteria and plant essential oil mixture on the generation of N-nitrosamines in deli meat during storage [PDF]

open access: yesFood Chemistry: X
To reduce the risk of N-nitrosamines in deli meat products, this study formulated a novel non-contact N-nitrosamines inhibiting preservative IV (NIP-IV) consisting of biocontrol bacteria and plant essential oils (EOs) (Stenotrophomonas rhizophila SR-1 ...
Ke Li   +9 more
doaj   +2 more sources

N-nitrosamines in processed meats: Exposure, formation and mitigation strategies

open access: yesJournal of Agriculture and Food Research, 2023
Nitrite and nitrate have been widely used in the preservation of meat products for the effective antimicrobial action against several pathogenic bacteria such as Clostridium botulinum, Salmonella and mesophilic bacteria.
Yingfeng Xie   +7 more
doaj   +1 more source

NMR Assignments of Six Asymmetrical N-Nitrosamine Isomers Determined in an Active Pharmaceutical Ingredient by DFT Calculations

open access: yesMolecules, 2022
N-nitrosamines, which are well-known pro-mutagens, are found in drugs, pickled food and tobacco. Therefore, controlling their concentrations is very important.
Hao-Yue Guan   +4 more
doaj   +1 more source

Development of a sensitive and stable GC-MS/MS method for simultaneous determination of four N-nitrosamine genotoxic impurities in sartan substances

open access: yesJournal of Analytical Science and Technology, 2021
Recently, N-nitrosamines have been unexpectedly found in generic sartan products. Herein, we developed a sensitive and stable GC-MS/MS method with multiple reactions monitoring mode for the simultaneous determination of four N-nitrosamines in sartan ...
Jie Liu   +8 more
doaj   +1 more source

Determination of dietary exposure and extraction efficiency of nitrosamine from cooked meat

open access: yesCurrent Research in Food Science, 2022
Meat products are claimed to be a source of carcinogenic nitrosamines (NAs) exposure in food. In this study, dietary exposure of six nitrosamines: N-nitrosodimethylamine (NDMA), N-nitrosodiethylamine (NDEA), N-nitrosopyrrolidine (NPYR), N ...
Abu Tareq Mohammad Abdullah   +4 more
doaj   +1 more source

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