Genomic Characterization of Urethritis-Associated Neisseria meningitidis Shows that a Wide Range of N. meningitidis Strains Can Cause Urethritis [PDF]
ABSTRACT Neisseria meningitidis , typically a resident of the oro- or nasopharynx and the causative agent of meningococcal meningitis and meningococcemia, is capable of invading and colonizing the urogenital tract.
Kevin C, Magnus Unemo, Samo Jeverica
exaly +6 more sources
Genome wide expression profiling reveals suppression of host defence responses during colonisation by Neisseria meningitides but not N. lactamica. [PDF]
Both Neisseria meningitidis and the closely related bacterium Neisseria lactamica colonise human nasopharyngeal mucosal surface, but only N. meningitidis invades the bloodstream to cause potentially life-threatening meningitis and septicaemia.
Hazel En En Wong +4 more
doaj +4 more sources
N. meningitidis and TLR Polymorphisms: A Fascinating Immunomodulatory Network. [PDF]
N. meningitidis infections represent a global health problem that can lead to the development of serious permanent sequelae. Although the use of antibiotics and prevention via vaccination have reduced the incidence of meningococcal disease, our understanding regarding N.
Gianchecchi E +4 more
europepmc +7 more sources
Fratricide activity of MafB protein of N. meningitidis strain B16B6. [PDF]
BACKGROUND: Neisseria meningitidis is an inhabitant of the mucosal surfaces of the human nasopharynx. We recently demonstrated that the secreted meningococcal Two-partner secretion protein A (TpsA) is involved in interbacterial competition. The C-terminal end of the large TpsA protein contains a small toxic domain that inhibits the growth of target ...
Arenas J +6 more
europepmc +6 more sources
Investigation of invasive Neisseria meningitidis serogroup Y ST1466 case increases in New York State [PDF]
Bacterial meningitis and septicemia caused by Neisseria meningitidis is a serious infection that requires immediate medical attention and prompt treatment. In the United States, cases of N. meningitidis serogroup Y increased sharply in 2023, leading to a
Krithivasan Sankaranarayanan +11 more
doaj +2 more sources
We have developed a novel Neisseria meningitidis serogroup-specific loop-mediated isothermal amplification (LAMP) assay for six of the most common meningococcal serogroups (A, B, C, W, X, and Y).
Dong Wook Kim +2 more
exaly +3 more sources
Effect of penicillin and chloramphenicol on the growth and endotoxin release by N. meningitidis [PDF]
SUMMARYThe action of two antibiotics, penicillin and chloramphenicol, on bacterial growth and endotoxin liberation was studied in 18 strains of Neissevia meningitidis isolated from blood and CSF of patients with meningococcal infections. The antibiotics were administered both separately and in combined form in doses equivalent to 1 MIC and 100 MIC ...
Maria Cândida M. Mellado +5 more
openalex +4 more sources
The comparative population genetics of Neisseria meningitidis and Neisseria gonorrhoeae [PDF]
Neisseria meningitidis and N. gonorrhoeae are closely related pathogenic bacteria. To compare their population genetics, we compiled a dataset of 1,145 genes found across 20 N. meningitidis and 15 N. gonorrhoeae genomes. We find that N.
Lucile Vigué, Adam Eyre-Walker
doaj +5 more sources
Effect of a vaccine to prevent serogroup A N meningitidis epidemics in Africa. [PDF]
Meyer SA, Novak RT.
europepmc +4 more sources
Antimicrobial-Resistant Clonal Complex 11 Neisseria meningitidis–Associated Urethritis Cluster, Thailand [PDF]
Sexually transmitted infections clinics in Bangkok, Thailand, reported increasing numbers of men with Neisseria meningitidis–associated urethritis during 2017–2023.
John C. Cartee +16 more
doaj +2 more sources

