Results 31 to 40 of about 13,493,624 (211)
Molecular epidemiology of meningococcal disease in Northern Ghana [PDF]
, 2001 Meningococcal disease remains a major public health concern, especially in the African Meningitis Belt where large meningitis epidemics with attack rates of up to 500/100,000 recur every 8-12 years.
Gagneux, Sébastien
core +1 more source
Pyrophosphate-mediated iron acquisition from transferrin in Neisseria meningitidis does not require TonB activity. [PDF]
PLoS ONE, 2014 The ability to acquire iron from various sources has been demonstrated to be a major determinant in the pathogenesis of Neisseria meningitidis.
Francis Biville +3 more
doaj +1 more source
Angewandte Chemie, EarlyView.A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster +13 more
wiley +2 more sources
Nitro Reduction‐Based RNA Control and Ultrafast Release
Angewandte Chemie, EarlyView.A chemical RNA caging–uncaging strategy based on nitro reduction is described. Nitroaryl groups introduced via acylation temporarily block the functions of diverse RNAs in vitro and in living cells. Treatment with a diboronic acid–bipyridine mixture rapidly reduces the nitro groups, releasing RNAs and restoring their activity.
Yiran Zhao +6 more
wiley +2 more sources
Imunidade conferida por vacinas anti-meningocócicas Immunity confered by anti-meningococci vaccines
Revista de Saúde Pública, 1993 Em razão da recente epidemia de doença meningocócica causada por N. meningitidis B na Grande São Paulo, Brasil, foi feita revisão das epidemias dessa doença ocorridas no Brasil desde o início do século e uma análise das vacinas atuais contra N ...
Lucimar Gonçalves Milagres +1 more
doaj +3 more sources
Kiss and Run – Phosphoglycerol Modifications of N. Meningitidis Pili Mediate Detachment [PDF]
Frontiers in Microbiology, 2011 geneity with an increase in the number of residues bearing PG. They further report that inactivation of pptB and substitution of pilin serine residue 93 (a conserved and likely site of PG occupancy in strain 8013) led to an approximately two-fold increase in the number of bacteria found in aggregates.
Michael eKoomey +3 more
openaire +3 more sources
Frontiers in Microbiology, 2019 Neisseria meningitidis is a Gram-negative bacterium that asymptomatically colonizes the human nasopharyngeal mucosa. Pilus-mediated initial adherence of N. meningitidis to the epithelial mucosa is followed by the formation of three-dimensional aggregates,
Sara Sigurlásdóttir +4 more
doaj +1 more source
Microbial Diversity in the Human Mouth: Dominant Genera and their Interactions. [PDF]
, 2010 Investigations seeking definition of the microbial diversity present in the human oral cavity have been underway for many years. These investigations seek to define the normal microflora of the oral cavity, as well as the stability of the microflora ...
Fergusson, Stacey Victoria
core +6 more sources
Applied Sciences, 2020 Neisseria meningitidis is a commensal pathogen that causes infectious cerebrospinal disease in people of all ages. The multivariate role of six disease-causing polysaccharide serotypes is found to play a crucial role in developing vaccines (or general ...
Md. Shahedur Rahman +6 more
doaj +1 more source
Детские инфекции (Москва), 2021 Invasive meningococcal infection is a significant cause of death, reaching 80% in septic shock. The Pediatric Research and Clinical Center for Infectious Diseases (PRCCID) has developed an algorithm for the treatment of children with invasive ...
K. V. Markova +8 more
doaj +1 more source