Results 51 to 60 of about 45,542 (259)

Interactions between encapsulated Neisseria meningitidis and host cells [PDF]

, 2010
A major feature of Neisseria meningitidis is its ability to invade human brain meninges. To access the meninges, the bacteria must cross the blood-brain barrier (BBB), which is one of the tightest barriers in the body. Therefore, N.
Xavier Nassif
core   +5 more sources

N. meningitidis1681 is a member of the FinO family of RNA chaperones [PDF]

RNA Biology, 2010
The conjugative transfer of F-like plasmids between bacteria is regulated by the plasmid-encoded RNA chaperone, FinO, which facilitates sense - antisense RNA interactions to regulate plasmid gene expression. FinO was thought to adopt a unique structure, however many putative homologs have been identified in microbial genomes and are considered members ...
Steven, Chaulk, Jun, Lu, Kemin, Tan, David C, Arthur, Ross A, Edwards, Laura S, Frost, Andrzej, Joachimiak, J N Mark, Glover   +7 more
openaire   +2 more sources

Neisseria gonorrhoeae lipooligosaccharide glycan epitopes recognized by bactericidal IgG antibodies elicited by the meningococcal group B-directed vaccine, MenB-4C

Frontiers in Immunology
IntroductionOuter membrane vesicles (OMVs) of Neisseria meningitidis in the group B-directed vaccine MenB-4C (BexseroR) protect against infections with Neisseria gonorrhoeae. The immunological basis for protection remains unclear. N.
Yih-Ling Tzeng, Soma Sannigrahi, Ray Borrow, David S. Stephens, David S. Stephens   +4 more
doaj   +1 more source

Scaling-up vaccine production: implementation aspects of a biomass growth observer and controller [PDF]

, 2009
This study considers two aspects of the implementation of a biomass growth observer and specific growth rate controller in scale-up from small- to pilot-scale bioreactors towards a feasible bulk production process for whole-cell vaccine against whooping ...
Boxtel, A.J.B., van, IJssel, J., van den, Pol, L.A., van der, Soons, Z.I.T.A., Straten, G., van   +4 more
core   +2 more sources

Susceptibility of Neisseria meningitidis and Neisseria gonorrhoeae isolates to N-formimidoyl thienamycin [PDF]

Antimicrobial Agents and Chemotherapy, 1982
A diverse collection of 123 meningococcal and 126 gonococcal isolates was tested for susceptibility to N-formimidoyl thienamycin (N-F-thienamycin; MK0787) and to penicillin G (PEN). All of the meningococci were susceptible to both of these, as well as to rifampin.
E J, Dudek, J D, Stephenson, M, Bohnhoff, S A, Lerner   +3 more
openaire   +2 more sources

Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock, Jin Nakahara, Becky Parks, Kerstin Allen, Sami Fam   +4 more
wiley   +1 more source

Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects

Advanced Science, EarlyView.
Bacterial outer membrane vesicles (OMVs) have emerged as versatile platforms for cancer vaccine development owing to their intrinsic immunostimulatory properties and high engineering flexibility. This review summarizes OMV biology, immune mechanisms, and engineering strategies that enhance vaccine efficacy, discusses key translational challenges, and ...
Jiabeini Zhang, Tianyu Shao, Fengjiang Qu, Caiyun Bai, Sijie Li, Pin Gao, Wenna Li, Keman Cheng, Xiao Zhao, Zhimin Fan   +9 more
wiley   +1 more source

Asymptomatic carriers of Neisseria meningitidis and Moraxella catarrhalis in healthy children

New Microbes and New Infections, 2020
There is a close correlation between asymptomatic oropharyngeal colonization by bacterial pathogens and paediatric respiratory diseases. Evaluation of the frequency of asymptomatic carriers of Neisseria meningitidis and Moraxella catarrhalis in healthy ...
A. Maleki, Z. Mirnaseri, E. Kouhsari, M. Taherikalani, I. Pakzad, J. Mohammadi, N. Sadeghifard   +6 more
doaj   +1 more source

Development of Multi-Locus Variable Number Tandem Repeat Analysis for Outbreak Detection of Neisseria meningitidis [PDF]

, 2006
Neisseria meningitidis is a major cause of septicemia and meningitis worldwide. Traditional typing methods like pulsed-field gel electrophoresis (PFGE) for identifying outbreaks are subjective and time consuming.
Price, Alicia Anne
core  

Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification [PDF]

, 2016
Filamentation induced by cyclic AMP (FIC)-domain enzymes catalyze adenylylation or other posttranslational modifications of target proteins to control their function.
Aragão, Hugo, Burmann, Björn M., Dehio, Christoph, Harms, Alexander, Hiller, Sebastian, Mazur, Adam, Schirmer, Tilman, Sharpe, Timothy, Stanger, Frédéric V.   +8 more
core   +1 more source