Results 41 to 50 of about 851 (135)

Epidemiological characteristics of invasive meningococcal disease and carriage prevalence of Neisseria meningitidis in the Xinjiang Uygur Autonomous Region, China, 2004–2023: a retrospective study [PDF]

PeerJ
Objective The Xinjiang Uygur Autonomous Region (Xinjiang) currently exhibits the high incidence rates of invasive meningococcal disease (IMD) in China.
Halimubieke Nazhaerbieke, Wenhui Fu, Zhaoguo Lan, Yesitai Muheiyati, Tian Tian, Caipilima Wuqierjiafu, Na Xie   +6 more
doaj   +2 more sources

Differential activation of acid sphingomyelinase and ceramide release determines invasiveness of Neisseria meningitidis into brain endothelial cells. [PDF]

PLoS Pathogens, 2014
The interaction with brain endothelial cells is central to the pathogenicity of Neisseria meningitidis infections. Here, we show that N. meningitidis causes transient activation of acid sphingomyelinase (ASM) followed by ceramide release in brain ...
Alexander Simonis, Sabrina Hebling, Erich Gulbins, Sibylle Schneider-Schaulies, Alexandra Schubert-Unkmeir   +4 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Genetic characterization of Neisseria meningitidis isolates recovered from patients with invasive meningococcal disease in Lithuania

Frontiers in Cellular and Infection Microbiology
IntroductionNeisseria meningitidis is a gram-negative bacterium responsible for life-threatening invasive infections known as invasive meningococcal disease and is associated with high fatality rates and serious lifelong disabilities among survivors ...
Anželika Slavinska, Magdalena Kowalczyk, Agnė Kirkliauskienė, Greta Vizuje, Paweł Siedlecki, Joana Bikulčienė, Kristina Tamošiūnienė, Aurelija Petrutienė, Nomeda Kuisiene   +8 more
doaj   +1 more source

Airway Mucus Restricts Neisseria meningitidis Away from Nasopharyngeal Epithelial Cells and Protects the Mucosa from Inflammation

mSphere, 2019
Neisseria meningitidis is an inhabitant of the nasopharynx, from which it is transmitted from person to person or disseminates in blood and becomes a harmful pathogen. In this work, we addressed colonization of the nasopharyngeal niche by focusing on the
Mathilde Audry, Catherine Robbe-Masselot, Jean-Philippe Barnier, Benoit Gachet, Bruno Saubaméa, Alain Schmitt, Sophia Schönherr-Hellec, Renaud Léonard, Xavier Nassif, Mathieu Coureuil   +9 more
doaj   +1 more source

Symptomatic Vaginal Infection by Neisseria meningitidis Resulting in Meningitis with Septic Shock

Clinical Practice and Cases in Emergency Medicine, 2019
The most common infectious etiologies of vaginitis include Gardnerella bacterial vaginosis, candidiasis, and trichomoniasis. A few case reports describe symptomatic infection with Neisseria (N) meningitidis, an organism with potential for causing ...
Ryan Offman, Elissa Boggs, Adam Gwizdala
doaj   +1 more source

Application of multiple-locus variable number tandem repeat analysis to identify outbreak-associated Neisseria meningitides serogroup C sequence type 4821 in China. [PDF]

PLoS ONE, 2015
Neisseria meningitidis (N. meningitidis) serogroup C sequence type (ST)-4821 caused an outbreak in 2010 in Shandong province of China. Twenty-one non-outbreak-associated strains were isolated, along with twenty-eight N.
Xiaoying Shan, Haijian Zhou, Ji Zhang, Bingqing Zhu, Li Xu, Guangchun Hu, Aiying Bai, Zhujun Shao, Baofa Jiang   +8 more
doaj   +1 more source

[Neuraminidase activity of N. meningitidis].

Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1976
The work was aimed at the study of the neuraminidase activity of meningococci. The optimal conditions for detection of this enzyme in meningococci were chosen preliminarily. In experiments carried out with the observance of these conditions it was shown that meningococci of the main serological groups possessed neuraminidase activity revealed in the ...
G V, Zhuravleva, A A, Demina, A M, Gracheva   +2 more
openaire   +1 more source

Purification of Disassembled Capsid Protein by Hydroxyapatite Chromatography Enhances Virus‐Like Particle Recovery

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Virus‐like particles (VLPs) are a promising modality with extensive applications in prophylactic and therapeutic vaccine design. Human Papillomavirus (HPV) vaccines are one such example where VLP vaccine applications have led to the successful reduction in HPV‐associated diseases, such as cervical cancer.
Nicholas Samuelson, Nathaniel Parker, Shiyi Wang, Sara Daley, Aaron Cote, Michael A. Winters   +5 more
wiley   +1 more source

Investigation of invasive Neisseria meningitidis serogroup Y ST1466 case increases in New York State

Frontiers in Public Health
Bacterial meningitis and septicemia caused by Neisseria meningitidis is a serious infection that requires immediate medical attention and prompt treatment. In the United States, cases of N. meningitidis serogroup Y increased sharply in 2023, leading to a
Krithivasan Sankaranarayanan, Andrew Peifer, Catharine Prussing, Elizabeth Owuor Bielli, Evan Owens, Kate Wahl, Anna Kidney, Wolfgang Haas, Aaditya Ojha, Caila B. Vaughn, Kimberlee A. Musser, Kara Mitchell   +11 more
doaj   +1 more source