Results 131 to 140 of about 28,700 (263)

The exposomal imprint on rosacea: More than skin deep

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki, Daniella Bakoli Sgourou, Alexandros Maniatis, Efstathia Pasmatzi   +3 more
wiley   +1 more source

Molecular Simulations Matching Denaturation Experiments for N6‑Methyladenosine

ACS Central Science, 2022
Valerio Piomponi, Thorben Fröhlking, Mattia Bernetti, Giovanni Bussi   +3 more
doaj   +1 more source

RNA N6-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m6A-GLUT1-mTORC1 Axis and Is a Therapeutic Target [PDF]

, 2020
Huarong Chen, Shanshan Gao, Weixin Liu, Chi-Chun Wong, Jianfeng Wu, Jingtong Wu, Dabin Liu, Hongyan Gou, Wei Kang, Jianning Zhai, Chuangen Li, Hao Su, Shiyan Wang, Fraser Soares, Jiahuai Han, Housheng Hansen He, Jun Yu   +16 more
openalex   +1 more source

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source

Combining metabolomics and 16S rRNA sequencing to investigate the effects of fecal microbiota transplantation intervention in aging mice

Journal of Holistic Integrative Pharmacy
Aging is a complex physiological process, accompanied by metabolic and immune disorders leading to aging. The aging process yields dramatic alterations in the gut microbiota. However, there is limited evidence for a mechanistic role of the gut microbiota
Tianxin Zhu, Ling Yang, Zhizhong Luo, Jiqian He, Xuefeng Xu, Duosheng Luo   +5 more
doaj   +1 more source

N6-methyladenosine demethylase FTO promotes growth and metastasis of gastric cancer via m6A modification of caveolin-1 and metabolic regulation of mitochondrial dynamics [PDF]

, 2022
You Zhou, Qi Wang, Haifeng Deng, Bin Xu, Yi Zhou, Jian Liu, Yingting Liu, Yufang Shi, Xiao Zheng, Jingting Jiang   +9 more
openalex   +1 more source

The Dual Role of the 16mer Motif Within the 3′ Untranslated Region of the Variant Surface Glycoprotein of Trypanosoma brucei

Molecular Microbiology, EarlyView.
A fully conserved 16mer motif is required in the silent VSG to trigger efficient silencing of the expression site (ES)‐resident VSG and a successful exchange of the VSG coat. ABSTRACT The variant surface glycoprotein (VSG) of African trypanosomes is essential for the survival of bloodstream form parasites.
Majeed Bakari‐Soale, Christopher Batram, Henriette Zimmermann, Nicola G. Jones, Markus Engstler   +4 more
wiley   +1 more source

Transcriptome-wide N6-Methyladenosine Methylome Profiling Reveals m6A Regulation of Skeletal Myoblast Differentiation in Cattle (Bos taurus)

, 2021
Xinran Yang, Jianfang Wang, Xinhao Ma, Jiawei Du, Chugang Mei, Linsen Zan   +5 more
openalex   +1 more source

Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy [PDF]

, 2020
Gaocai Li, Yu Song, Zhiwei Liao, Kun Wang, Rongjin Luo, Saideng Lu, Kangcheng Zhao, Xiaobo Feng, Hang Liang, Liang Ma, Bingjin Wang, Wencan Ke, Huipeng Yin, Shengfeng Zhan, Shuai Li, Xinghuo Wu, Yukun Zhang, Yang Cao   +17 more
openalex   +1 more source

The RNA m6A Methyltransferase PvFIP37 Activates Vacuole Transport and Glutathione Detoxification Pathways to Increase Switchgrass Cd Tolerance

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cadmium (Cd) pollution is a growing global issue that poses significant threats to ecosystems and human health. N6‐methyladenosine (m6A) plays an essential role in regulating plant growth and stress responses, but the biological functions and regulatory mechanisms of m6A core enzymes under Cd stress remain largely unexplored. In this study, we
Mengzhuo Lin, Lei Wang, Bowen Liu, Huayue Liu, Wenwu Qian, Die Zhou, Hui Zang, Binglin Hong, Yunwei Zhang, Jishan Jiang   +9 more
wiley   +1 more source