Results 121 to 130 of about 53,902 (279)

DataSheet5_Comprehensive Analysis of N6-Methyladenosine-Related Long Noncoding RNA Prognosis of Acute Myeloid Leukemia and Immune Cell Infiltration.ZIP

, 2022
N6-Methyladenosine-related long noncoding RNAs play an essential role in many cancers’ development. However, the relationship between m6A-related lncRNAs and acute myelogenous leukemia (AML) prognosis remains unclear.
Xiting Cao (4169698), Yongli Yang (5142224), Xuezhong Shi (11434753), Guowei Zheng (603754), Mengying Liu (2149954), Ani Dong (11689711), Junna Xie (12498481), Jie Lu (139953), Yang Zhao (39052), Huili Zhu (310323), Dongsheng Hu (394136), Xinyu Chang (9334455), Wanli Hu (4502581), Xiaocan Jia (11434747)   +13 more
core   +1 more source

RBMS1 Contributes to Early Arteriovenous Fistula Neointimal Remodeling Through Modulation of VSMC Phenotypic Responses

Advanced Science, EarlyView.
Postoperative arteriovenous fistulas exhibit increased RBMS1 in vascular smooth muscle cells (VSMCs). In experimental AVFs, RBMS1 overexpression aggravates, whereas deletion attenuates, neointimal hyperplasia. RBMS1 binds MPZL1 mRNA and promotes exon 5 skipping to generate MPZL1‐Δ5, which interacts with G3BP1 to activate AKT, driving VSMC proliferation,
Zongda Li, Chengwei Zhang, Xinying Yu, Shuang Yao, Yiting Lai, Xiaozhu Sun, Yao Zhao, Xiaoyu Lan, Tingting Hu, Wenjin Li, Zhenzhen Ma, Huimin Ma, Zihan Wang, Haihai Liang, Jundong Jiao   +14 more
wiley   +1 more source

Association of N6-methyladenosine with viruses and related diseases

Virology Journal, 2019
AbstractBackgroundN6-methyladenosine (m6A) modification is the most prevalent internal modification of eukaryotic mRNA modulating gene expression. m6A modification is a dynamic reversible process regulated by three protein groups: methyltransferases (writers), demethylases (erasers), and m6A-binding proteins (readers).
Fang Wu, Wenzhao Cheng, Feiyuan Zhao, Mingqing Tang, Yong Diao, Ruian Xu   +5 more
openaire   +3 more sources

Table_1_Identification of N6-Methyladenosine-Related lncRNAs as a Prognostic Signature in Glioma.docx

, 2022
N6-methyladenosine (m6A) modification is the most abundant modification in long noncoding RNAs (lncRNAs). Current studies have shown that the abnormal expression of m6A-related genes is closely associated with the tumorigenesis and progression of glioma.
Shenglun Li (11976044), Weihai Ning (7540880), Yujia Chen (844413), Yuduo Guo (9638345), Lixin Ma (18620), Jiacheng Xu (3629917), Hongwei Zhang (28335), Xiang Wang (127867), Mingshan Zhang (6956762), Yanming Qu (11976047)   +9 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Image_4_Identification of N6-Methyladenosine-Related lncRNAs as a Prognostic Signature in Glioma.tif

, 2022
N6-methyladenosine (m6A) modification is the most abundant modification in long noncoding RNAs (lncRNAs). Current studies have shown that the abnormal expression of m6A-related genes is closely associated with the tumorigenesis and progression of glioma.
Shenglun Li (11976044), Weihai Ning (7540880), Yujia Chen (844413), Yuduo Guo (9638345), Lixin Ma (18620), Jiacheng Xu (3629917), Hongwei Zhang (28335), Xiang Wang (127867), Mingshan Zhang (6956762), Yanming Qu (11976047)   +9 more
core   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

The role of N6-methyladenosine modification in tumor angiogenesis

Frontiers in Oncology
Tumor angiogenesis is a characteristics of malignant cancer progression that facilitates cancer cell growth, diffusion and metastasis, and has an indispensable role in cancer development. N6-methyladenosine (m6A) is among the most prevalent internal modifications in eukaryotic RNAs, and has considerable influence on RNA metabolism, including its ...
Lifei Qin, Xinya Zeng, Xinze Qiu, Xingmei Chen, Shiquan Liu   +4 more
openaire   +3 more sources

Image_2_Identification of N6-Methyladenosine-Related lncRNAs as a Prognostic Signature in Glioma.tif

, 2022
N6-methyladenosine (m6A) modification is the most abundant modification in long noncoding RNAs (lncRNAs). Current studies have shown that the abnormal expression of m6A-related genes is closely associated with the tumorigenesis and progression of glioma.
Shenglun Li (11976044), Weihai Ning (7540880), Yujia Chen (844413), Yuduo Guo (9638345), Lixin Ma (18620), Jiacheng Xu (3629917), Hongwei Zhang (28335), Xiang Wang (127867), Mingshan Zhang (6956762), Yanming Qu (11976047)   +9 more
core   +1 more source

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source