Results 111 to 120 of about 1,821,119 (298)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Interaction Study between Umami and Salty Based on Electronic Tongue Technology and σ-τ Model

open access: yesShipin gongye ke-ji
Salt and salty foods play a crucial role in enhancing flavor and are integral to traditional cuisine. Salt control and intake reduction are particularly important in a sodium reduction policy. To investigate the relationship between umami ingredients and
Linxue DAI   +4 more
doaj   +1 more source

Evaluation of a new extraction system for rapid measurement of surface lipid content of rice for degree of milling estimation [PDF]

open access: yes, 2003
Few fruit thinners have been certified for organic fruit growers. Previous studies have shown that herbicides or shade are capable of reducing photosynthesis and are effective fruit-thinning techniques, although impractical. This project evaluated use of
Parker, Amanda   +2 more
core   +2 more sources

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

open access: yesFEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani   +7 more
wiley   +1 more source

Salt crystallization dynamics in building rocks: a 4D study using laboratory X-ray micro-CT [PDF]

open access: yes, 2015
We employ laboratory X-ray micro-computed tomography (μCT) during climate-controlled salt weathering experiments to acquire data on the kinetics of drying and salt precipitation and the distribution of crystals within the pore space of Mšené sandstone ...
Boone, Marijn   +9 more
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

STUDI PROPORSI TEPUNG PORANG : TAPIOKA DAN PENAMBAHAN NaCl TERHADAP KARAKTERISTIK FISIK BAKSO SAPI

open access: yesJurnal Pangan dan Agroindustri, 2014
Tepung porang dari umbi porang (Amorphophallus muelleri Blume) memiliki kandungan glukomanan yang tinggi. Glukomanan merupakan serat larut memiliki kemampuan membentuk gel.
Nimas Ratu Kali Dewi   +1 more
doaj  

Design, Fabrication, and Testing of Salt Spray as An Atmospheric Corrosion Test Tool Using MgCl₂ and NaCl Solutions

open access: yesJurnal Kimia Sains dan Aplikasi
The research aimed to design a salt spray chamber adhering to ASTM-B117 standards and test the chamber with determine the atmospheric corrosion rate in a salt spray chamber using steel materials (ST 37 and SS 304) in NaCl and MgCl2 solutions.
Sri Hastuty   +4 more
doaj   +1 more source

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